Results 51 to 60 of about 1,705 (213)
GRAFT: Unsupervised Adaptation to Resizing for Detection of Image Manipulation
IEEE Access, 2020 A large number of methods for forensics of image manipulation relies on detecting fingerprints in residuals or noises. Therefore, these detection methods are bound to be sensitive to noise generated by the image acquisition process, as well as any pre ...
Ludovic Darmet, Kai Wang, Francois Cayre
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
AISMSNet: Advanced Image Splicing Manipulation Identification Based on Siamese Networks
Applied SciencesThe exponential surge in specialized image editing software has intensified visual forgery, with splicing attacks emerging as a popular forgery technique.
Ana Elena Ramirez-Rodriguez +4 more
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Image Manipulation with Perceptual Discriminators [PDF]
, 2018 Systems that perform image manipulation using deep convolutional networks have achieved remarkable realism. Perceptual losses and losses based on adversarial discriminators are the two main classes of learning objectives behind these advances. In this work, we show how these two ideas can be combined in a principled and non-additive manner for ...
Diana Sungatullina +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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FEDNet: A feature-enhanced diffusion network for efficient and universal texture synthesis
Computational Visual MediaTexture synthesis remains challenging due to the complex and varied nature of texture characteristics. To address this issue, this paper introduces a feature-enhanced diffusion network, FEDNet, which achieves both fidelity and diversity through two core ...
Haichuan Song +2 more
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source