Results 51 to 60 of about 710,329 (341)
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Supernova Educator's Guide [PDF]
, 2008 This educator’s guide features three curriculum enhancement activities and one scientific literacy activity, extensive background information, assessment rubrics, student worksheets, extension and transfer activities, and detailed information about the ...
core
Acts of Time: Cohen and Benjamin on Mathematics and History [PDF]
, 2017 This paper argues that the principle of continuity that underlies Benjamin’s understanding of what makes the reality of a thing thinkable, which in the Kantian context implies a process of “filling time” with an anticipatory structure oriented to the ...
Ng, Julia
core +1 more source
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Zoom invariant vision of figural shape: The mathematics of cores [PDF]
, 1998 Believing that figural zoom invariance and the cross-figural boundary linking implied by medial loci are important aspects of object shape, we present the mathematics of and algorithms for the extraction of medial loci directly from image intensities ...
Bryan S. Morse +3 more
core +3 more sources
FEBS Open Bio, EarlyView.This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source
Students’ Evolving Meaning About Tangent Line with the Mediation of a Dynamic Geometry Environment and an Instructional Example Space [PDF]
, 2011 In this paper I report a lengthy episode from a teaching experiment in which fifteen Year 12 Greek students negotiated their definitions of tangent line to a function graph.
A Bell +25 more
core +1 more source
Mathematical Methods in Biomedical Imaging 2014 [PDF]
Computational and Mathematical Methods in Medicine, 2014 The last quarter century has witnessed major advancements that have brought biomedical imaging to a paramount status in life sciences. Generally speaking, the scope of biomedical imaging covers data acquisition, image reconstruction, and image analysis, involving theories, methods, systems, and applications. While many kinds of imaging modalities, such
Peng Feng +3 more
openaire +3 more sources
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source