Results 201 to 210 of about 11,444,505 (290)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard   +3 more
wiley   +1 more source

Odon: an ultra-fast viewer for spatial proteomics. [PDF]

open access: yesBioinformatics
Coulton A, McGranahan N.
europepmc   +1 more source

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH‐1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode‐derived cells in the brain

open access: yesDevelopmental Dynamics, EarlyView.
Abstract The olfactory placode (OP) generates a broad array of chemosensory neurons in the nasal region, including olfactory sensory neurons, vomeronasal sensory neurons, neurons of the septal organ, and Grueneberg ganglion. During invagination, the OP also generates migratory neuronal populations, including gonadotropin‐releasing hormone‐1 (GnRH‐1 ...
Enrico Amato Jr.   +5 more
wiley   +1 more source

Phenotypic overlap masking MELAS in Turner syndrome: a diagnostic challenge. [PDF]

open access: yesEur Heart J Case Rep
Shinozaki T   +4 more
europepmc   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová   +5 more
wiley   +1 more source

MIT/TFE family transcription factors, Mitf and Tfec, redundantly promote pigment cell differentiation and retinal epithelium pigmentation in teleosts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Transcription factors of the MIT/TFE family—mitfa, mitfb, and tfec—play essential roles in specifying pigment cells derived from neural crest cells in vertebrates. In teleosts, which possess multiple pigment cell types, these factors exhibit partially redundant but largely distinct functions across different pigment lineages.
James Lister   +13 more
wiley   +1 more source

Climate‐driven resource availability drives medium‐ and broad‐scale temporal changes in owl–prey interactions over 24 years in a semi‐arid ecosystem

open access: yesEcography, EarlyView.
Predator–prey interactions are vital to ecosystem functioning but may be disrupted by climate change. We investigated a food‐web network involving three owl species over 24 years in a semi‐arid ecosystem at Bosque Fray Jorge National Park, Chile.
Jazmin M. Quiroz‐Calizaya   +12 more
wiley   +1 more source

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