Results 71 to 80 of about 319,555 (318)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Model-Based Feature Extraction for Gait Analysis and Recognition [PDF]

open access: yes, 2007
Human motion analysis has received a great attention from researchers in the last decade due to its potential use in different applications. We propose a new approach to extract human joints (vertex positions) using a model-based method. Motion templates
BOUCHRIKA, I, NIXON, M S
core  

Using Scene‐Flow to Improve Predictions of Road Users in Motion With Respect to an Ego‐Vehicle

open access: yesIET Intelligent Transport Systems
We addressed the challenge of accurately determining the motion status of vehicles neighbouring an ego‐vehicle, across various driving scenarios. The aim was to enhance the prediction accuracy in identifying moving vehicles through the integration of ...
Nilusha Jayawickrama   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Markerless Feature Extraction for Gait Analysis [PDF]

open access: yes, 2006
Human motion analysis has received a great attention from researchers in the last decade due to its potential use in different applications. We propose a new approach to extract human joints (Vertex positions)using a model-based method.
NIXON, M. S., BOUCHRIKA, I.
core  

Simplified and approximation autofocus back-projection algorithm for SAR

open access: yesThe Journal of Engineering, 2019
Due to accuracy limited inertial measurement unit systems, residual synthetic aperture radar (SAR) motion errors need to be compensated by autofocus method. Back-projection (BP) algorithm is a time-domain imaging process suitable for arbitrary trajectory
Zhenyu Guo, Hongbo Zhang, Shaohua Ye
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Contrast-Independent Biologically Inspired Motion Detection [PDF]

open access: yes, 2011
Babies B, Lindemann JP, Egelhaaf M, Möller R. Contrast-Independent Biologically Inspired Motion Detection. Sensors. 2011;11(12):3303-3326.Optic flow, i.e., retinal image movement resulting from ego-motion, is a crucial source of information used for ...
Lindemann, Jens Peter ; https://orcid.org/   +7 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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