Results 101 to 110 of about 555,997 (285)

Medical image computing and computer-aided medical interventions applied to soft tissues. Work in progress in urology

open access: yes, 2006
Until recently, Computer-Aided Medical Interventions (CAMI) and Medical Robotics have focused on rigid and non deformable anatomical structures. Nowadays, special attention is paid to soft tissues, raising complex issues due to their mobility and ...
Bart, Stéphane   +18 more
core   +1 more source

SVM Classification of MRI Brain Images for Computer-Assisted Diagnosis

open access: yes, 2017
Magnetic Resonance Imaging is a powerful technique that helps in the diagnosis of various medical conditions. MRI Image pre-processing followed by detection of brain abnormalities, such as brain tumors, are considered in this work. These images are often
M. Hamiane, Fatema Saeed
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

A Comparison of Radiographic Film Densitometry Using a New Computerized Tool with a Digital Densitometer

open access: yesFrontiers in Dentistry, 2016
Objectives: The purpose of this study was to develop and test a new tool for radiographic densitometry by combining periapical films and aluminum step wedge. Materials and Methods: We reviewed 50 Kodak E-speed intraoral films.
Hoorieh Bashizadeh Fakhar   +3 more
doaj  

The effectiveness of automatic laparoscopic diagnostics of liver pathology using different methods of digital images classification

open access: yesPatologìâ, 2017
Сomputer automatic diagnostic (CAD)/classification of video – images is actual for laparoscopic surgery. Such CAD is supposed to explore intraoperatively for support surgeon decisions. Aim: to evaluate the effectiveness of the CAD systems developed on
D. N. Bayazitov   +2 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Assessment of Human Sperm Kinematic Parameters Using Computer-Assisted Semen Analysis

open access: yesHittite Journal of Science and Engineering
Infertility affects approximately 15% of couples trying to conceive, as reported by the World Health Organization. It is diagnosed when conception does not occur despite unprotected intercourse over the course of at least one ...
Nazlı Irmak Karaark, Hüseyin Kurtuldu
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

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