Results 81 to 90 of about 376,443 (285)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Digital mammography, cancer screening: Factors important for image compression [PDF]

open access: yes
The use of digital mammography for breast cancer screening poses several novel problems such as development of digital sensors, computer assisted diagnosis (CAD) methods for image noise suppression, enhancement, and pattern recognition, compression ...
Blaine, G. James   +7 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Automatic Apparent Nasal Index from Single Facial Photographs Using a Lightweight Deep Learning Pipeline: A Pilot Study

open access: yesMedicina
Background and Objectives: Quantifying nasal proportions is central to facial plastic and reconstructive surgery, yet manual measurements are time-consuming and variable.
Babak Saravi   +10 more
doaj   +1 more source

Implementation of ILLIAC 4 algorithms for multispectral image interpretation [PDF]

open access: yes
Research has focused on the design and partial implementation of a comprehensive ILLIAC software system for computer-assisted interpretation of multispectral earth resources data such as that now collected by the Earth Resources Technology Satellite ...
Donovan, W. E.   +3 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

CIE L*a*b*: comparison of digital images obtained photographically by manual and automatic modes

open access: yesBrazilian Oral Research, 2012
The aim of this study was to analyze the color alterations performed by the CIE L*a*b* system in the digital imaging of shade guide tabs, which were obtained photographically according to the automatic and manual modes.
Fabiana Takatsui   +4 more
doaj  

Removing defocused objects from single focal plane scans of cytological slides

open access: yesJournal of Pathology Informatics, 2016
Background: Virtual microscopy and automated processing of cytological slides are more challenging compared to histological slides. Since cytological slides exhibit a three-dimensional surface and the required microscope objectives with high resolution ...
David Friedrich   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

From image-guided surgery to surgeOmics: Facing the era of intelligent automation and robotics

open access: yesInternational Journal of Gastrointestinal Intervention, 2019
Digital images do not represent anatomy, they are just a reliable translation from a full-colored and three-dimensional physical world to a grayscale and two dimensions image domain.
Juan Manuel Verde, Mariano E. Giménez
doaj   +1 more source

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