Results 121 to 130 of about 94,524 (266)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

<i>In vivo</i> photoacoustic imaging of swine ureters injected with methylene blue. [PDF]

J Biomed Opt
Arroyo J, Zhang J, Zhang J, Venkatayogi N, Kakkar M, Maxwell A, Gabrielson K, Lediju Bell MA.   +7 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Transformer-assisted convolutional feature extraction with deep representation learning models for lung and colon cancer diagnosis using histopathological images. [PDF]

Sci Rep
Jayanthi S, Kaur I, Laxmi Lydia E, Kumar KV, Joshi GP, Cho W.   +5 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Ultrafast visual perception beyond human capabilities enabled by motion analysis using synaptic transistors. [PDF]

Nat Commun
Wang S, Zhao J, Pu T, Zhao L, Guo X, Cheng Y, Li C, Ma W, Tang C, Xu Z, Wang N, Occhipinti LG, Nathan A, Dahiya R, Wu H, Tao L, Gao S.   +16 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Clinical application research of navigation system-assisted vertebroplasty for the treatment of lumbar osteoporotic compression fractures. [PDF]

BMC Surg
Lian Y, Xie Y, Yu H, Xuan A, Wei Y, Wang Z, Xiang L, Gu H.   +7 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

All-Optical Diffractive Operators for Rapid, Computer-Free Morphological Transformations. [PDF]

Nanophotonics
Sun Y, Wang F, Han J, Qu G, Zhang Z, Wei Y, Yang C, Ruan Q, Wang S, Wei H, Huang C, Guan J, Hu J.   +12 more
europepmc   +1 more source