Results 171 to 180 of about 539,757 (266)

Application of artificial intelligence in medical imaging for tumor diagnosis and treatment: a comprehensive approach. [PDF]

Discov Oncol
Huang J, Xiang Y, Gan S, Wu L, Yan J, Ye D, Zhang J.   +6 more
europepmc   +1 more source

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

Advanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe, Samantha Kaonis, Natalie Calahan, Neda Kabi, Soham Ghosh   +4 more
wiley   +1 more source

Using Masked Image Modelling Transformer Architecture for Laparoscopic Surgical Tool Classification and Localization. [PDF]

Sensors (Basel)
ElMoaqet H, Janini R, Ryalat M, Al-Refai G, Abdulbaki Alshirbaji T, Jalal NA, Neumuth T, Moeller K, Navab N.   +8 more
europepmc   +1 more source

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

Combining multimodal medical imaging and artificial intelligence for the early diagnosis of pancreatic cancer. [PDF]

Front Med (Lausanne)
Yu X, Wang Y, Wang Y, Feng J, Fan S, Li C.   +5 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Frequency domain manipulation of multiple copy-move forgery in digital image forensics. [PDF]

PLoS One
Qazi T, Shah M, Ali M, Gul F, Ahmad M, Khan A.   +5 more
europepmc   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

A deep learning framework for automated early diagnosis and classification of skin cancer lesions in dermoscopy images. [PDF]

Sci Rep
Al-Waisy AS, Al-Fahdawi S, Khalaf MI, Mohammed MA, Al-Attar B, Al-Andoli MN.   +5 more
europepmc   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source