Results 71 to 80 of about 813,438 (205)

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Morphometric analysis of neurons from the marginal and substantia gelatinosa layers of human spinal cord: Classification according to laminar organization [PDF]

Vojnosanitetski Pregled, 2005
The main goal of morphometric analysis of neuronal images, except for getting information about their geometry and dendritic branching patterns, is their classification based on laminar organization.
Milošević Nebojša T., Ristanović Dušan S., Stanković Jovan B., Nedeljkov Vladimir B.   +3 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

From image-guided surgery to surgeOmics: Facing the era of intelligent automation and robotics

International Journal of Gastrointestinal Intervention, 2019
Digital images do not represent anatomy, they are just a reliable translation from a full-colored and three-dimensional physical world to a grayscale and two dimensions image domain.
Juan Manuel Verde, Mariano E. Giménez
doaj   +1 more source

Reduce Noise in Computed Tomography Image using Adaptive Gaussian Filter [PDF]

arXiv, 2019
One image processing application that is very helpful for humans is to improve image quality, poor image quality makes the image more difficult to interpret because the information conveyed by the image is reduced. In the process of the acquisition of medical images, the resulting image has decreased quality (degraded) due to external factors and ...
arxiv  

Quarter Laplacian Filter for Edge Aware Image Processing [PDF]

arXiv, 2021
This paper presents a quarter Laplacian filter that can preserve corners and edges during image smoothing. Its support region is $2\times2$, which is smaller than the $3\times3$ support region of Laplacian filter. Thus, it is more local. Moreover, this filter can be implemented via the classical box filter, leading to high performance for real time ...
arxiv  

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Mammographic Image Enhancement using Digital Image Processing Technique [PDF]

arXiv, 2018
Abstract PURPOSES this study aims to perform microcalsification detection by performing image enhancement in mammography image by using transformation of negative image and histogram equalization. image mammography with .pgm format changed to. jpg format then processed into negative image result then processed again using histogram equalization.
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Removing defocused objects from single focal plane scans of cytological slides

Journal of Pathology Informatics, 2016
Background: Virtual microscopy and automated processing of cytological slides are more challenging compared to histological slides. Since cytological slides exhibit a three-dimensional surface and the required microscope objectives with high resolution ...
David Friedrich, Alfred Böcking, Dietrich Meyer-Ebrecht, Dorit Merhof   +3 more
doaj   +1 more source