Results 101 to 110 of about 2,859,172 (249)

Canopy imaging spectroscopy reveals a stepwise redshifted energy redistribution in the antenna under drought stress

open access: yesScientific Reports
There is a consensus on the role of protein conformational changes within the photosynthetic antenna that alter the spectral properties of the embedded pigments during regulated heat dissipation, but despite this, the molecular mechanisms involved are ...
Clara García-Martínez   +6 more
doaj   +1 more source

MEDICAL IMAGE PROCESSING USING MATLAB [PDF]

open access: yes
MATLAB and the Image Processing Toolbox provide a wide range of advanced image processing functions and interactive tools for enhancing and analyzing digital images. The interactive tools allowed us to perform spatial image transformations, morphological
Emilia Dana SELEŢCHI
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Image data processing system requirements study. Volume 1: Analysis [PDF]

open access: yes
Digital image processing, image recorders, high-density digital data recorders, and data system element processing for use in an Earth Resources Survey image data processing system are studied.
Honikman, T.   +4 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Detection of elliptical polarization parameters using a metalens

open access: yesКомпьютерная оптика
A metalens capable of detecting the polarization ellipticity of an incident beam is considered in this paper. This metalens consists of blocks with diffraction gratings of a 140-nm height and a 220-nm period.
A.G. Nalimov   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Photographic image enhancement and processing [PDF]

open access: yes
Image processing techniques (computer and photographic) are described which are used within the JSC Photographic Technology Division. Two purely photographic techniques used for specific subject isolation are discussed in detail.
Lockwood, H. E.
core   +1 more source

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