Results 81 to 90 of about 2,910,023 (339)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Multi-Focus Image Fusion Through Gradient- Based Decision Map Construction and Mathematical Morphology

IEEE Access, 2016
Multi-focus image fusion is an important technique that extracts sharp regions from multiple images and composites them into a fully focused image. In this paper, a novel spatial domain-based fusion algorithm for multi-focus images through gradient-based
Xiangzhi Bai, Miaoming Liu, Zhiguo Chen, Peng Wang, Yu Zhang   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Airport Detection Using End-to-End Convolutional Neural Network with Hard Example Mining

Remote Sensing, 2017
Deep convolutional neural network (CNN) achieves outstanding performance in the field of target detection. As one of the most typical targets in remote sensing images (RSIs), airport has attracted increasing attention in recent years.
Bowen Cai, Zhiguo Jiang, Haopeng Zhang, Danpei Zhao, Yuan Yao   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Gaussian Process Regression Hybrid Models for the Top-of-Atmosphere Retrieval of Vegetation Traits Applied to PRISMA and EnMAP Imagery

Remote Sensing
The continuous monitoring of the terrestrial Earth system by a growing number of optical satellite missions provides valuable insights into vegetation and cropland characteristics.
Ana B. Pascual-Venteo, Jose L. Garcia, Katja Berger, José Estévez, Jorge Vicent, Adrián Pérez-Suay, Shari Van Wittenberghe, Jochem Verrelst   +7 more
doaj   +1 more source

Partial Color Photo Processing Method for Components Based on Image Enhancement Technology [PDF]

, 2021
Hao Wu, Zhi Zhou
openalex   +1 more source

Consumer attitudes and expectations of organic wine [PDF]

, 2008
Within the European Union-funded research project ORWINE (Organic viticulture and wine-making) a qualitative consumer study was carried out in 2006 in the four case study countries Italy, France, Germany and Switzerland.
Schmid, Otto, Stolz, Hanna
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Loopy belief propagation and probabilistic image processing [PDF]

, 2003
Estimation of hyperparameters by maximization of the marginal likelihood in probabilistic image processing is investigated by using the cluster variation method.
Inoue, J., Tanaka, K., Titterington, M.
core