Utilisation of Objective and Subjective Image Quality Metrics to Guide Optimal Contrast Volumes for Abdominal CT. [PDF]
Carrick D +6 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Enhanced image quality in head and neck MRI with PROPELLER and deep learning reconstruction. [PDF]
Takano Y +9 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Dual-scan conformal cone-beam CT for targeted image-quality improvement using dynamic collimation. [PDF]
Liu Y, Yuan S, Feng X, Dai J.
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Correction to "Improving image quality in terbium-161 phantom imaging: Quantitative evaluation of DEW and TEW scatter correction methods". [PDF]
europepmc +1 more source
Application of Deep Learning Algorithm-Based Image Reconstruction in Improving Abdominal CT Image Quality in Adrenal and Renal Lesions Detection. [PDF]
Tian J +7 more
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Correction to: Deep learning-based motion correction: cardiac motion artifact and image quality improvements on chest CT. [PDF]
Ozawa Y +10 more
europepmc +1 more source

