Results 161 to 170 of about 1,683,057 (326)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Application of 80-kVp scan and raw data-based iterative reconstruction for reduced iodine load abdominal–pelvic CT in patients at risk of contrast-induced nephropathy referred for oncological assessment: effects on radiation dose, image quality and renal function

, 2018
Yasunori Nagayama, Shota Tanoue, Akinori Tsuji, Joji Urata, M Furusawa, Seitaro Oda, Takeshi Nakaura, Daisuke Utsunomiya, Eri Yoshida, Morikatsu Yoshida, Masafumi Kidoh, Machiko Tateishi, Yasuyuki Yamashita   +12 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Consistent explainable image quality assessment for medical imaging. [PDF]

Health Inf Sci Syst
Ozer C, Guler A, Turkvatan Cansever A, Oksuz I.   +3 more
europepmc   +1 more source

Quality Assessment for Secondary Use of Imaging Trials [PDF]

Friederike Seyderhelm, Felix Balzer, Alaa Bejaoui, Maria Bosserdt, James Bowden, Marc Dewey, Bernhard Föllmer, Heiko Tzschätzsch, Norman Zerbe, Dagmar Krefting   +9 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

AI-based image quality assessment of positioning in mammography: considerations and challenges. [PDF]

Insights Imaging
Santner T, Tardy M, Stalheim JG, Frei S, Santner W, Gianolini S, Galijasevic M, Larsen M, Gjesvik J, Hofvind S, Widmann G.   +10 more
europepmc   +1 more source

[LS2N_IPI] IRCCyN IVC Quality Assessment Of Stereoscopic Images

Alexandre Benoit, Patrick Le callet, P. Campisi, Romain Cousseau   +3 more
openalex   +1 more source

Quality Prediction of DWT‐Based Compression for Remote Sensing Image Using Multiscale and Multilevel Differences Assessment Metric [PDF]

, 2014
Hongxu Jiang, Kai Yang, Tingshan Liu, Yongfei Zhang   +3 more
openalex   +1 more source