Results 221 to 230 of about 1,688,289 (276)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Review of Image Quality Assessment Methods for Compressed Images. [PDF]

J Imaging
Jamil S.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

ConIQA: A deep learning method for perceptual image quality assessment with limited data. [PDF]

Sci Rep
Eybposh MH, Cai C, Moossavi A, Rodriguez-Romaguera J, Pégard NC.   +4 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

No-Reference Image Quality Assessment Combining Swin-Transformer and Natural Scene Statistics. [PDF]

Sensors (Basel)
Yang Y, Lei Z, Li C.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

QualityNet: A multi-stream fusion framework with spatial and channel attention for blind image quality assessment. [PDF]

Sci Rep
Aslam MA, Wei X, Khalid H, Ahmed N, Shuangtong Z, Liu X, Xu Y.   +6 more
europepmc   +1 more source

IQAGPT: computed tomography image quality assessment with vision-language and ChatGPT models. [PDF]

Vis Comput Ind Biomed Art
Chen Z, Hu B, Niu C, Chen T, Li Y, Shan H, Wang G.   +6 more
europepmc   +1 more source

Enhancing Radiological Diagnosis: A Comprehensive Review of Image Quality Assessment and Optimization Strategies. [PDF]

Cureus
Varghese AP, Naik S, Asrar Up Haq Andrabi S, Luharia A, Tivaskar S.   +4 more
europepmc   +1 more source