Results 81 to 90 of about 12,998,590 (302)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A Robust Iris Segmentation Scheme Based on Improved U-Net

IEEE Access, 2019
Iris segmentation plays an important role in the iris recognition system, and the accurate segmentation of iris can lay a good foundation for the follow-up work of iris recognition and can improve greatly the efficiency of iris recognition.
Wei Zhang, Xiaoqi Lu, Yu Gu, Yang Liu, Xianjing Meng, Jing Li   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Control and Synchronization of Julia Sets of the Discrete Three-Dimensional Fractional HCV Model

Fractal and Fractional
This paper investigates the fractal dynamical behavior of a discrete Caputo fractional-order hepatitis C virus model. First, we analyze the stability of the system by using spectral radius and design the fractional-order controller based on coordinate ...
Miao Ouyang, Yang Chen, Yuan Jiang, Junhua Li, Shutang Liu   +4 more
doaj   +1 more source

Feature learning via partial differential equation with applications to face recognition

, 2017
Feature learning is a critical step in pattern recognition, such as image classification. However, most of the existing methods cannot extract features that are discriminative and at the same time invariant under some transforms.
Fang, Cong, Zhao, Zhenyu, Lin, Zhouchen, Zhou, Pan, Pan Zhou, Zhouchen Lin, Zhenyu Zhao, Cong Fang   +7 more
core   +1 more source

Active exploration and keypoint clustering for object recognition [PDF]

, 2008
Object recognition is a challenging problem for artificial systems. This is especially true for objects that are placed in cluttered and uncontrolled environments. To challenge this problem, we discuss an active approach to object recognition. Instead of
Bart de Boer, Kootstra, Gert, de Boer, Bart,, De Boer, B., de Boer, Bart, Kootstra, G.W., Kootstra, G., Ypma, Jelmer,, Kootstra, Gert,, Ypma, J., Ypma, Jelmer, Gert Kootstra, Ypma, J, Jelmer Ypma   +13 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Multitraining support vector machine for image retrieval [PDF]

, 2006
Relevance feedback (RF) schemes based on support vector machines (SVMs) have been widely used in content-based image retrieval (CBIR). However, the performance of SVM-based RF approaches is often poor when the number of labeled feedback samples is small.
Tao, D., Li, J, Li, X, Li, J., Li, Xuelong, Allinson, N., Allinson, N, Tao, D   +7 more
core   +1 more source