Results 91 to 100 of about 2,163,711 (277)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MathematicsTraditional sparse coding has proven to be an effective method for image feature representation in recent years, yielding promising results in image classification.
Ying Shi +3 more
doaj +1 more source
Structured Knowledge Representation for Image Retrieval
Journal of Artificial Intelligence Research, 2002 We propose a structured approach to the problem of retrieval of images by content and present a description logic that has been devised for the semantic indexing and retrieval of images containing complex objects. As other approaches do, we start from low-level features extracted with image analysis to detect and characterize regions
Di Sciascio, E. +2 more
openaire +5 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Digital image representation by atomic functions: features for computer vision and machine learning
Авіаційно-космічна техніка та технологіяDigital images obtained from remote sensing (RS) systems have become essential in numerous technological applications across diverse domains, including environmental monitoring, agriculture, urban planning, and defense.
Viktor Makarichev +3 more
doaj +1 more source
High-efficiency scene classification based on deep compressed-domain feature
The Journal of Engineering, 2019 Remote sensing image (RSI) scene classification has become a more and more fundamental issue in satellite and UAV time-sensitive applications. However, as the volume and velocity of RSIs are undergoing an explosive growth, traditional effective ...
Cheng Li +4 more
doaj +1 more source
Sparse Representation For Image Prediction
, 2007 Publication in the conference proceedings of EUSIPCO, Poznan, Poland ...
Martin, Aurélie +3 more
openaire +2 more sources