Results 101 to 110 of about 2,182,891 (278)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Tibetan Data Augmentation via GAN‐Based Handwritten Text Generation

open access: yesCAAI Transactions on Intelligence Technology
Increased awareness of Tibetan cultural preservation, along with technological advancements, has led to significant efforts in academic research on Tibetan.
Dorje Tashi   +9 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Incorporation of Histogram Intersection and Semantic Information into Non-Negative Local Laplacian Sparse Coding for Image Classification

open access: yesMathematics
Traditional sparse coding has proven to be an effective method for image feature representation in recent years, yielding promising results in image classification.
Ying Shi   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Digital image representation by atomic functions: features for computer vision and machine learning

open access: yesАвіаційно-космічна техніка та технологія
Digital images obtained from remote sensing (RS) systems have become essential in numerous technological applications across diverse domains, including environmental monitoring, agriculture, urban planning, and defense.
Viktor Makarichev   +3 more
doaj   +1 more source

High-efficiency scene classification based on deep compressed-domain feature

open access: yesThe Journal of Engineering, 2019
Remote sensing image (RSI) scene classification has become a more and more fundamental issue in satellite and UAV time-sensitive applications. However, as the volume and velocity of RSIs are undergoing an explosive growth, traditional effective ...
Cheng Li   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Join multiple Riemannian manifold representation and multi‐kernel non‐redundancy for image clustering

open access: yesCAAI Transactions on Intelligence Technology
Image clustering has received significant attention due to the growing importance of image recognition. Researchers have explored Riemannian manifold clustering, which is capable of capturing the non‐linear shapes found in real‐world datasets.
Mengyuan Zhang, Jinglei Liu
doaj   +1 more source

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