Results 131 to 140 of about 2,182,891 (278)
A self-supervised contrastive learning approach for whole slide image representation in digital pathology. [PDF]
J Pathol Inform, 2022 Fashi PA +4 more
europepmc +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
A Review of Adaptive Image Representations
IEEE Journal of Selected Topics in Signal Processing, 2011 Improving the modeling of natural images is important to go beyond the state-of-the-art for many image processing tasks such as compression, denoising, inverse problems, and texture synthesis. Natural images are composed of intricate patterns such as regular areas, edges, junctions, oriented oscillations, and textures.
openaire +3 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Image representation of the acoustic signal: An effective tool for modeling spectral and temporal dynamics of connected speech. [PDF]
J Acoust Soc Am, 2022 Ghasemzadeh H, Doyle PC, Searl J.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Cyber-Threat Detection System Using a Hybrid Approach of Transfer Learning and Multi-Model Image Representation. [PDF]
Sensors (Basel), 2022 Ullah F +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Bearing Fault Diagnosis Based on an Enhanced Image Representation Method of Vibration Signal and Conditional Super Token Transformer. [PDF]
Entropy (Basel), 2022 Li J +6 more
europepmc +1 more source