Results 51 to 60 of about 93,063 (265)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Photographing of a Radiograph: A Simple Alternative
Photograph of a radiograph is customarily shot using "X-ray viewer" as a background. However, it has its own disadvantages in quality reproduction of image details.
Matrishva B Vyas, Navin V Hantodkar
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Image clustering is a critical and essential component of image analysis to several fields and could be considered as an optimization problem. Cuckoo Search (CS) algorithm is an optimization algorithm that simulates the aggressive reproduction strategy ...
Kaouter Labed +3 more
doaj +1 more source
Appearance reproduction and multispectral imaging [PDF]
AbstractWith the recent progress of broadband networks, accurate appearance reproduction across various environments is required for objects in various applications such as e‐commerce, the designing process, and telemedicine. Multispectral imaging techniques are expected to perform cross‐environment color reproduction for objects.
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
La carte postale, multiple documentaire du chef-d’œuvre
From the late nineteenth century to the 1970s, to the “era of technical reproducibility” of works of art, in Europe as in the United States, postcard reproductions constituted mass imagery and a cultural industry, by helping to produce “multiples” of ...
Bertrand Tillier
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

