Results 121 to 130 of about 7,150,154 (369)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

MSTNet: a multi-stage progressive network with local–global transformer fusion for image restoration

Complex & Intelligent Systems
Image restoration is a challenging and complex problem involving recovering the original clear image from a degraded or noisy image. In the medical field, image restoration techniques can significantly improve the quality of endoscopic images, helping ...
Ruyu Liu, Lin Wang, Jie He, Jiajia Wang, Jianhua Zhang, Xiufeng Liu, Chaochao Wang, Haoyu Zhang, Sheng Dai   +8 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Optimum constrained image restoration filters [PDF]

The filter was developed in Hilbert space by minimizing the radius of gyration of the overall or composite system point-spread function subject to constraints on the radius of gyration of the restoration filter point-spread function, the total noise ...
Mcgillem, C. D., Riemer, T. E.
core   +1 more source

Hybrid regularization inspired by total variation and deep denoiser prior for image restoration

Complex & Intelligent Systems
Image restoration is a fundamental problem in computer vision, with the goal of restoring high-quality images from degraded low-quality observation images. However, the ill-posedness of restoration problem often leads to artifacts in the results.
Hu Liang, Jiahao Zhang, Daisen Wei, Jinbo Zhu   +3 more
doaj   +1 more source

The Effects of AI-Driven Face Restoration on Forensic Face Recognition

Applied Sciences
In biometric recognition, face recognition is a mature and widely used technique that provides a fast, accurate, and reliable method for human identification.
Mengxuan Yang, Shengnan Li, Jinhua Zeng
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Structured FISTA for image restoration

Numerical Linear Algebra with Applications, 2019
SummaryIn this paper, we propose an efficient numerical scheme for solving some large‐scale ill‐posed linear inverse problems arising from image restoration. In order to accelerate the computation, two different hidden structures are exploited. First, the coefficient matrix is approximated as the sum of a small number of Kronecker products.
Zixuan Chen, James G. Nagy, Yuanzhe Xi, Bo Yu   +3 more
openaire   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Restoration of above canopy reference hemispherical image from below canopy measurements for plant area index estimation in forests/ Metsa võrastiku läbipaistvuse mõõtmine digitaalsete poolsfäärikaamerate abil [PDF]

, 2013
Mait Lang, Ave Kodar, Tauri Arumäe
openalex   +1 more source