Results 91 to 100 of about 11,514,111 (239)

Singularities of noncommutative surfaces [PDF]

, 2018
The primary objects of study in this thesis are noncommutative surfaces; that is, noncommutative noetherian domains of GK dimension 2. Frequently these rings will also be singular, in the sense that they have infinite global dimension.
Crawford, Simon Philip
core   +2 more sources

Puzzling Out the Zodiacal Disk of Brindisi

Pallas
The zodiacal disk of Brindisi has long been at the center of a debate regarding its dating. In this study, I will attempt not only to propose a new date but also to explain its iconographic singularities. In the overall production of zodiacal images, the
Fabio Spadini
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Stroke Subtype Clustering by Multifractal Bayesian Denoising with Fuzzy C Means and K-Means Algorithms

Complexity, 2018
Multifractal denoising techniques capture interest in biomedicine, economy, and signal and image processing. Regarding stroke data there are subtle details not easily detectable by eye physicians.
Yeliz Karaca, Carlo Cattani, Majaz Moonis, Şengül Bayrak   +3 more
doaj   +1 more source

The optical singularities of birefringent dichroic chiral crystals

, 2003
Using a new formalism involving projection from the sphere of directions to the stereographic plane, and associated complex variables, explicit formulae are obtained for the two refractive indices and polarizations in optically anisotropic crystals that ...
Dennis, MR, Berry, MV, M. V. Berry, Dennis, M.R., M. R. Dennis, Berry, M.V., Berry, M. V., Dennis, M. R.; id_orcid   +7 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Polarization singularities in the clear sky

, 2004
Ideas from singularity theory provide a simple account of the pattern of polarization directions in daylight. The singularities (two near the Sun and two near the anti-Sun) are points in the sky where the polarization line pattern has index +1/2 and the ...
R L Lee, Dennis, MR, Berry, MV, Lee, Jr, R.L., M R Dennis, M V Berry, Lee Jr, RL, Dennis, M.R., Berry, M V, Dennis, M R; id_orcid, Lee, R L, Berry, M.V.   +11 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Quantum state evolution and Berry potentials at exceptional points and quantum phase transitions

New Journal of Physics
The behavior of quantum states at exceptional points (EPs) and at critical points associated with quantum phase transitions (QPTs) is intriguing yet puzzling.
Chia-Yi Ju, Fu-Hsiang Huang
doaj   +1 more source

Nonlocal Extensions of First Order Initial Value Problems

Axioms
We study certain Volterra integral equations that extend and recover first order ordinary differential equations (ODEs). We formulate the former equations from the latter by replacing classical derivatives with nonlocal integral operators with anti ...
Ravi Shankar
doaj   +1 more source