Results 101 to 110 of about 7,328,187 (296)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Quantum state evolution and Berry potentials at exceptional points and quantum phase transitions
New Journal of PhysicsThe behavior of quantum states at exceptional points (EPs) and at critical points associated with quantum phase transitions (QPTs) is intriguing yet puzzling.
Chia-Yi Ju, Fu-Hsiang Huang
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Nonlocal Extensions of First Order Initial Value Problems
AxiomsWe study certain Volterra integral equations that extend and recover first order ordinary differential equations (ODEs). We formulate the former equations from the latter by replacing classical derivatives with nonlocal integral operators with anti ...
Ravi Shankar
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Multifractal imaging filtering and decomposition methods in space, Fourier frequency, and eigen domains [PDF]
Nonlinear Processes in Geophysics, 2007 The patterns shown on two-dimensional images (fields) used in geosciences reflect the end products of geo-processes that occurred on the surface and in the subsurface of the Earth.
Qiuming Cheng
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Forum of Mathematics, PiSuppose J=(f1,…,fn) $J = (f_1, \dots , f_n)$ upper J equals left parenthesis f 1 comma ellipsis comma f Subscript n Baseline right parenthesis is an n-generated ideal in any ring R.
Linquan Ma +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source