Results 91 to 100 of about 13,391,983 (260)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Transcatheter arterial and venous embolisation with α-hexyl cyanoacrylate MagicGlue®: short-term safety and efficacy outcomes

CVIR Endovascular
Purpose Our purpose was to assess the feasibility and the short-term safety and efficacy outcomes of a wide range of transcatheter arterial and venous embolisation procedures done using α-hexyl-cyanoacrylate (AHCA)-MagicGlue® in patients with bleeding ...
Hamza Sawalha, Olivier Chevallier, Mohamed Fouad, Taninokuchi Tomassini Makoto, Comby Pierre-Olivier, Ludwig Serge Aho-Glele, Romaric Loffroy   +6 more
doaj   +1 more source

Neuronal variability reflects probabilistic inference tuned to natural image statistics. [PDF]

Nat Commun, 2021
Festa D, Aschner A, Davila A, Kohn A, Coen-Cagli R.   +4 more
europepmc   +1 more source

Department of Applied Mathematics and Statistics Newsletter, December 8, 2025

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

core  

Department of Applied Mathematics and Statistics Newsletter, November 17, 2025 [PDF]

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Perception of visual advertising in different media: from attention to distraction, persuasion, preference and memory

Frontiers in Psychology, 2014
Jaana eSimola, Jukka eHyönä, Jarmo eKuisma   +2 more
doaj   +1 more source

Perceived roughness of glossy objects: The influence of Fresnel effects and correlated image statistics. [PDF]

J Vis, 2021
Faul F.
europepmc   +1 more source

Department of Applied Mathematics and Statistics Newsletter, February 9, 2026

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source