Results 81 to 90 of about 550,068 (301)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Image Denoising by Statistical Area Thresholding [PDF]
Journal of Mathematical Imaging and Vision, 2005 Area openings and closings are morphological filters which efficiently suppress impulse noise from an image, by removing small connected components of level sets. The problem of an objective choice of threshold for the area remains open. Here, a mathematical model for random images will be considered.
Coupier, David +2 more
openaire +3 more sources
Variational image registration using inhomogeneous regularization [PDF]
, 2014 We present a generalization of the convolution basedvariational image registration approach, in which differentregularizers can be implemented by conveniently exchangingthe convolution kernel, even if it is nonseparableor nonstationary.
Albrecht, Thomas +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Robust Statistical Fusion of Image Labels [PDF]
IEEE Transactions on Medical Imaging, 2012 Image labeling and parcellation (i.e., assigning structure to a collection of voxels) are critical tasks for the assessment of volumetric and morphometric features in medical imaging data. The process of image labeling is inherently error prone as images are corrupted by noise and artifacts.
Bennett A. Landman +5 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
i-Perception, 2021 The visual system represents textural image regions as simple statistics that are useful for the rapid perception of scenes and surfaces. What images ‘textures’ are, however, has so far mostly been subjectively defined. The present study investigated the
Fumiya Kurosawa +3 more
doaj +1 more source
Image denoising with directional bases [PDF]
, 2007 Directional information is an important component of both natural and synthetic images, and it is exploited in many image processing applications. Directional basis analysis is used to capture significant structural information.
Park, Heechan +3 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source