Results 101 to 110 of about 14,589,261 (282)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Masked Style Transfer for Source-Coherent Image-to-Image Translation

open access: yesApplied Sciences
The goal of image-to-image translation (I2I) is to translate images from one domain to another while maintaining the content representations. A popular method for I2I translation involves the use of a reference image to guide the transformation process ...
Filippo Botti   +3 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Feature Consistency-Based Style Transfer for Landscape Images Using Dual-Channel Attention

open access: yesIEEE Access
With the rapid development of artificial intelligence technology, style transfer has become an important topic in current research. However, existing models are deficient in fusing content and style features, resulting in a large gap between the ...
Qiang Zhang, Shuai Wang, Dong Cui
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Extending user control for image stylization using hierarchical style transfer networks

open access: yesHeliyon
The field of neural style transfer refers to the re-rendering of content image while fusing the features of a style image. The recent studies either focus on multiple style transfer or arbitrary style transfer while using perceptual and fixpoint content ...
Sunder Ali Khowaja   +7 more
doaj   +1 more source

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