Results 151 to 160 of about 621,417 (312)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

View synthesis for depth from motion 3D x-ray imaging.

open access: yes, 2009
The depth from motion or kinetic depth X-ray imaging (KDEX) technique is designed to enhance the luggage screening at airport checkpoints. The technique requires multiple views of the luggage to be obtained from an arrangement of linear X-ray detector ...
Liu, Y
core  

The cosparse analysis model and algorithms

open access: yes, 2013
After a decade of extensive study of the sparse representation synthesis model, we can safely say that this is a mature and stable field, with clear theoretical foundations, and appealing applications.
Gribonval, Rémi   +8 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Towards Colour Imaging with the Image Ranger

open access: yes, 2006
Many of the colour images captured by different types of digital camera do not provide quality colour image according to human visual perception. In this study we explore technique for colour correction of the colour images from the Waikato Image Ranger.
Muttayane, Anandajothi
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

The multiresolution Fourier transform : a general purpose tool for image analysis [PDF]

open access: yes
The extraction of meaningful features from an image forms an important area of image analysis. It enables the task of understanding visual information to be implemented in a coherent and well defined manner.
Calway, Andrew David
core  

Directional edge and texture representations for image processing [PDF]

open access: yes, 2007
An efficient representation for natural images is of fundamental importance in image processing and analysis. The commonly used separable transforms such as wavelets axe not best suited for images due to their inability to exploit directional ...
Yao, Zhen
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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