Results 151 to 160 of about 1,181,367 (337)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Modified ESRGAN with Uformer for Video Satellite Imagery Super-Resolution

open access: yesRemote Sensing
In recent years, a growing number of sensors that provide imagery with constantly increasing spatial resolution are being placed on the orbit. Contemporary Very-High-Resolution Satellites (VHRS) are capable of recording images with a spatial resolution ...
Kinga Karwowska, Damian Wierzbicki
doaj   +1 more source

To assess the value of satellite photographs in resource evaluation on a national scale [PDF]

open access: yes
The author has identified the following significant results. The limit of resolution on ERTS imagery is normally acknowledged to be about 60 miles although very long features such as roads and railways which are often less than 10 miles long are easily ...
Hepworth, J. V., Hutton, S. M.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Simulation evaluation of display/FLIR concepts for low-altitude, terrain-following helicopter operations [PDF]

open access: yes
A piloted simulation of three head-down display (HDD) concepts with flight-director guidance superimposed on forward-looking infrared (FLIR) imagery was performed to evaluate the task of low-level, terrain-following (TF), manual helicopter flight.
Kilmer, F. G.   +3 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Assessment of satellite and aircraft multispectral scanner data for strip-mine monitoring [PDF]

open access: yes
The application of LANDSAT multispectral scanner data to describe the mining and reclamation changes of a hilltop surface coal mine in the rugged, mountainous area of eastern Kentucky is presented.
Dooley, J. T., Spisz, E. W.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Practical application of remote sensing in agriculture [PDF]

open access: yes
Remote sensing program imagery from several types of platforms, from light aircraft to the LANDSAT (ERTS) satellites, have been utilized during the past few years, with preference for inexpensive imagery over expensive magnetic tapes.
Phelps, R. A.
core   +1 more source

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