Results 71 to 80 of about 10,409,633 (267)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Images for Iconoclasts: Images of Confucius in the Cultural Revolution
, 2007 Confucius died and was buried in 479 B.C.E., and he was never seen again. Or so one would think. “You may forget me as I once was,” Confucius reminds us in the Zhuangzi, but there is something unforgettable about me that will still live on. Confucius’s
Sommer, Deborah A., (司馬黛蘭)
core
Computational ghost imaging using deep learning
, 2017 Computational ghost imaging (CGI) is a single-pixel imaging technique that exploits the correlation between known random patterns and the measured intensity of light transmitted (or reflected) by an object.
Endo, Yutaka +10 more
core +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Images of Power, Images of War: Schmucker Art Gallery’s New Exhibit
, 2016 Bodies in Conflict: From Gettysburg to Iraq is a brand new exhibit in Schmucker Art Gallery at Gettysburg College. Curated by Mellon Summer Scholar Laura Bergin ’17, it features eleven depictions of bodies engaged in various conflicts in U.S.
Wilson, Laurel J.
core
NEFI: Network Extraction From Images
, 2015 Networks and network-like structures are amongst the central building blocks of many technological and biological systems. Given a mathematical graph representation of a network, methods from graph theory enable a precise investigation of its properties.
Dirnberger, Michael +2 more
core +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Radiology Case ReportsTerminal 7q deletion is a rare chromosomal anomaly resulting from partial deletion of the long arm of chromosome 7. 7q terminal deletion syndrome results in variable clinical phenotypes, such as microcephaly, holoprosencephaly, craniofacial abnormalities,
Kavita Aneja, MD, Sweta Krishnan, MD
doaj +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source