Results 71 to 80 of about 2,427,618 (287)

Art and Medicine: from anatomic studies to Visual Thinking Strategies [PDF]

open access: yes, 2015
Over the centuries the collaboration between artists and doctors and the relationship between art and medicine disciplines have been documented. Since the '60s the discipline of medical humanities has been developed in order to enrich the studies in ...
De Santis, Sara   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Wavelet Features for Recognition of First Episode of Schizophrenia from MRI Brain Images [PDF]

open access: yes, 2014
Machine learning methods are increasingly used in various fields of medicine, contributing to early diagnosis and better quality of care. These outputs are particularly desirable in case of neuropsychiatric disorders, such as schizophrenia, due to the ...
Dluhos, P., Kasparek, T., Schwarz, D.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Potency by Name? ‘Medicine Buddha Plant’ and Other Herbs in the Japanese \u3ci\u3eScroll of Equine Medicine\u3c/i\u3e (\u3ci\u3eBa’i sōshi emaki\u3c/i\u3e, 1267) [PDF]

open access: yes, 2019
Buddhist ritual healing and medical therapies included care for domestic animals, such as the horse. In pre-modern Japan, equine medicine (ba’i 馬医) was not restricted to the treatment of military horses; it was also practiced in a religious context.
Triplett, Katja
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Images in medicine. Diskitis [PDF]

open access: yesPostgraduate Medical Journal, 1998
Donckier, Julian, Delgrange, Etienne
openaire   +3 more sources

Petrography, The Tar Sands Paradise, and the Medium of Modernity [PDF]

open access: yes, 2016
This article engages with the artistic practice of petrography, the art of creating photographic images through the action of sunlight upon bitumen, the heavy-oil material that is the source of the petroleum in the Athabasca tar sands.
Cariou, Warren, Gordon, Jon
core   +1 more source

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