Results 1 to 10 of about 4,180 (201)

Construction of an easy-to-use predictive model for ultrasound-detected tophi to improve the detection of hidden tophi

open access: yesRheumatology & Autoimmunity, 2023
Background Musculoskeletal ultrasound is used in clinical practice to evaluate gout patients and is an effective imaging tool for the detection of tophi.
Hongchao Li, Hui Song, Wei Liu
exaly   +3 more sources

Gouty Tophi in Developed Countries: Uncovering Underlying Brain Diseases [PDF]

open access: yesDiagnostics
A 56-year-old man, accompanied by city hall staff, visited our neurorehabilitation clinic. Despite hyperuricemia being diagnosed several years ago, he refused treatment. He had no history of hypertension and antihypertensive drug use.
Koji Hayashi   +6 more
doaj   +3 more sources

Disseminated Chronic Tophaceous Gout With Multi-Tissue Involvement. [PDF]

open access: yesClin Case Rep
ABSTRACT Gout is a metabolic condition in which hyperuricaemia leads to deposition of monosodium urate (MSU) crystals in synovial and peri‐articular tissues. (1) Acutely, synovial deposition causes a painful inflammatory reaction. Over time, chronic hyperuricaemia can lead to deposition of uric acid crystals in alternate tissues, with granulomatous ...
Loh YL, Combe F.
europepmc   +2 more sources

Variations in the Management of Uncontrolled Gout Between Rheumatologists and Nephrologists: A Retrospective Medical Record Review. [PDF]

open access: yesACR Open Rheumatol
Objective To evaluate the management practices of rheumatologists and nephrologists in treating patients with uncontrolled gout. Methods US board‐certified rheumatologists and nephrologists treating patients with uncontrolled gout participated in a web‐based, retrospective medical record audit study, sharing their perceptions of uncontrolled gout ...
Saag K   +7 more
europepmc   +2 more sources

A retrospective analysis of the surgical efficacy for tophi wounds in Hainan province [PDF]

open access: yesFrontiers in Surgery
IntroductionGouty tophi are chronic inflammatory nodules resulting from monosodium urate (MSU) crystal deposition, often leading to joint deformity, skin ulceration, and functional impairment.
Weihao Xiao   +11 more
doaj   +2 more sources

A rare case presentation of a common condition: A large laryngeal gouty tophus [PDF]

open access: yesRadiology Case Reports
Laryngeal gout is an exceedingly rare manifestation of advanced, poorly controlled gout. It is characterized by the deposition of gouty tophi within various laryngeal structures. Similar to peripheral joints, monosodium urate crystals develop due to high
Habib Hassan, DO   +2 more
doaj   +2 more sources

Efficacy and Safety of Ultra-Low Starting Dose Febuxostat Titration in Male Patients With Primary Gout. [PDF]

open access: yesInt J Rheum Dis
ABSTRACT Background Since gout is a common metabolic arthritis caused by urate crystal deposition, urate‐lowering therapy (ULT) is clearly indicated, but the initiation of ULT frequently causes paradoxical acute flares that in turn impair patient adherence.
Huizhen S   +5 more
europepmc   +2 more sources

Asymptomatic Gouty Tophi in Thyroid Cartilage: A Case Report and Literature Review

open access: yesEar, Nose and Throat Journal
Gouty tophi is a disease characterized by the long-term deposition of monosodium urate crystals in joints or cartilages. The most commonly affected site is the first metatarsophalangeal joint, and gouty tophi in the head and neck region are relatively ...

exaly   +2 more sources

Exploring the inflammatory origins of gouty arthritis: mechanistic studies based on local lesion proteomics and validation [PDF]

open access: yesFrontiers in Immunology
BackgroundThe exact pathogenesis of gouty arthritis (GA) is unclear. However, it is believed that GA is characterized by recurrent episodes and a self-limiting nature.
Niqin Xiao   +14 more
doaj   +2 more sources

Gouty tophi in the thoracic spinal canal with incomplete paraplegia: a case report [PDF]

open access: yesFrontiers in Surgery
Gout manifesting in the spine is a relatively rare occurrence. Involvement of the lumbar spine is more common in cases of spinal gout, while reports of gouty tophi forming within the thoracic spinal canal are exceedingly rare. This article reports a case
Chunyu Zhao   +4 more
doaj   +2 more sources

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