Adjacent segment disease induced by spinal tophus: a case report [PDF]
Frontiers in SurgeryTophus, a hallmark feature of chronic gout, typically develops in the joints of the extremities, skin, and mucosal tissues. Although several case reports have described spinal tophus deposition leading to spinal stenosis and radiculopathy, documented ...
Chenglong Wang +7 more
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Elevated serum cystatin C predicts tophus formation in gout: evidence from a cross-sectional study [PDF]
Frontiers in EndocrinologyObjectiveTo investigate the association between serum cystatin C (CysC) levels and tophus presence, and to assess its diagnostic value for structural joint damage in gout.MethodsIn this cross-sectional study of 598 gout patients, we examined the ...
Yonglu Hu +8 more
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Gouty arthritis animal models: limitations, challenges, and optimization strategies [PDF]
Frontiers in Veterinary ScienceGouty arthritis (GA) is an inflammatory disease primarily triggered by the deposition of monosodium urate (MSU) crystals in and around the joints. With rising living standards and shifts in dietary patterns, the global incidence of GA is increasing ...
Huan Chen, Yu Zhang, Long Chen
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From uric acid to tophi: multistage molecular and cellular mechanisms of tophi formation [PDF]
Frontiers in ImmunologyTophus is a hallmark lesion of chronic gout, formed through the combined effects of monosodium urate (MSU) crystal deposition, persistent inflammation, and progressive tissue fibrosis. These lesions can cause joint deformities, functional impairment, and
Heguo Yan +18 more
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Coexistent gouty and infectious tenosynovitis in the hand: a case report and narrative review of comparable cases [PDF]
Case Reports in Plastic Surgery & Hand SurgeryAlthough less commonly in the hand, gouty tenosynovitis may present with symptoms resembling infection. Only a few case reports document such presentations, and reports of coexisting infection and gouty tenosynovitis are even more uncommon. A 32-year-old
Mohammad Nouri +3 more
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Kiesselbach’s area nasal septal gouty tophus with an integrated “3 + 2” diagnostic algorithm: a case report [PDF]
Journal of Medical Case ReportsBackground Gout, characterized by monosodium urate crystal deposition, rarely involves the nasal septum, with only a few reported cases. Such unusual presentations can mimic other conditions, necessitating prompt and accurate diagnosis.
Weikun Chen +5 more
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Gouty Tophi in Developed Countries: Uncovering Underlying Brain Diseases [PDF]
DiagnosticsA 56-year-old man, accompanied by city hall staff, visited our neurorehabilitation clinic. Despite hyperuricemia being diagnosed several years ago, he refused treatment. He had no history of hypertension and antihypertensive drug use.
Koji Hayashi +6 more
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Febuxostat may decrease the incidence of COVID-19 infection among patients with gout: a retrospective cohort study [PDF]
Frontiers in PharmacologyBackgroundAs COVID-19 infection causes a kidney proximal tubule dysfunction with urinary loss of uric acid. Hypouricemia has been found in patients with severe COVID-19 disease.
Weijie Wang +9 more
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Intra-articular Mass of the Knee by Gout Tophus: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2020 Gout is a relatively common condition in the population today. With progressing of the treatment of the hyperuricaemia, the case of producing a tophus decreases year by year.
Naoki Ishida, Ivan Sekiguchi
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Gender characteristics of gout and differences in response to taking xanthioxidase inhibitors
Медицинский совет, 2021 Introduction. To date, there is no consensus regarding the gender characteristics of the course of gout. There is little data on the possible difference between men and women in response to uric acid-lowering therapy.Aim.
V. V. Tsurko, M. A. Gromova
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