Results 51 to 60 of about 215,997 (243)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Multilayer Perceptron Mapping of Subjective Time Duration onto Mental Imagery Vividness and Underlying Brain Dynamics: A Neural Cognitive Modeling Approach

Machine Learning and Knowledge Extraction
According to a recent experimental phenomenology–information processing theory, the sensory strength, or vividness, of visual mental images self-reported by human observers reflects the intensive variation in subjective time duration during the process ...
Matthew Sheculski, Amedeo D’Angiulli
doaj   +1 more source

Assessing the Imagination Scale’s Nomological Validity: Effect of Hedonic versus Utilitarian Product Types and Abstract versus Concrete Advertising Execution

Gadjah Mada International Journal of Business, 2020
This research builds on a study of advertisement-evoked imagination scale developed by Dewi and Ang (2015). The imagination scale contains four types of imagination, that is, benefit-anticipatory imagination, emotional-bonding imagina­tion, symbolic ...
Ike Janita Dewi, Swee Hoon Ang
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The physical dimensions of the home learning environment and its impact on young people’s learning motivations

Cogent Education
This article brings a novel perspective to the relationship between the physical dimensions of Home Learning Environments (HLE) and young people’s learning motivations during COVID-19 pandemic in UK. The architectural/physical focus of this investigation
Ana Rute Costa
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Neural circuits for retrospective and prospective introspection for the past, present and future in macaque monkeys and humans

Neuroscience Research
For animals, including humans, to have self-awareness, the ability to reflect on one's own perceptions and cognitions, which is known as metacognition, and an understanding of consistency of the self from the past to the present and into the future based
Kentaro Miyamoto
doaj   +1 more source

Verbena speciosa 'Imagination' 'Imagination' Verbena

EDIS, 2007
The publication provides an overview of the ‘Imagination’ verbena, a perennial ground cover well-suited for Florida landscapes. This plant, which won the All American Selections award in 1993, features deep violet-blue or purple flowers that bloom in ...
Edward Gilman
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Epistemic Uses of Imagination

, 2021
This book explores a topic that has recently become the subject of increased philosophical interest: how can imagination be put to epistemic use? Though imagination has long been invoked in contexts of modal knowledge, in recent years philosophers have ...

core   +1 more source