Results 51 to 60 of about 179,692 (309)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Asymmetric projection of introspection reveals a behavioural and neural mechanism for interindividual social coordination

Nature Communications
When we collaborate with others to tackle novel problems, we anticipate how they will perform their part of the task to coordinate behavior effectively.
Kentaro Miyamoto, Caroline Harbison, Shiho Tanaka, Marina Saito, Shuyi Luo, Sara Matsui, Pranav Sankhe, Ali Mahmoodi, Mingming Lin, Nadescha Trudel, Nicholas Shea, Matthew F. S. Rushworth   +11 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Multilayer Perceptron Mapping of Subjective Time Duration onto Mental Imagery Vividness and Underlying Brain Dynamics: A Neural Cognitive Modeling Approach

Machine Learning and Knowledge Extraction
According to a recent experimental phenomenology–information processing theory, the sensory strength, or vividness, of visual mental images self-reported by human observers reflects the intensive variation in subjective time duration during the process ...
Matthew Sheculski, Amedeo D’Angiulli
doaj   +1 more source

Assessing the Imagination Scale’s Nomological Validity: Effect of Hedonic versus Utilitarian Product Types and Abstract versus Concrete Advertising Execution

Gadjah Mada International Journal of Business, 2020
This research builds on a study of advertisement-evoked imagination scale developed by Dewi and Ang (2015). The imagination scale contains four types of imagination, that is, benefit-anticipatory imagination, emotional-bonding imagina­tion, symbolic ...
Ike Janita Dewi, Swee Hoon Ang
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The physical dimensions of the home learning environment and its impact on young people’s learning motivations

Cogent Education
This article brings a novel perspective to the relationship between the physical dimensions of Home Learning Environments (HLE) and young people’s learning motivations during COVID-19 pandemic in UK. The architectural/physical focus of this investigation
Ana Rute Costa
doaj   +1 more source

Verbena speciosa 'Imagination' 'Imagination' Verbena

EDIS, 2007
The publication provides an overview of the ‘Imagination’ verbena, a perennial ground cover well-suited for Florida landscapes. This plant, which won the All American Selections award in 1993, features deep violet-blue or purple flowers that bloom in ...
Edward Gilman
doaj   +1 more source