Results 61 to 70 of about 4,405,442 (293)

Integrated system for ultrasonic, elasticity and photoacoustic imaging [PDF]

open access: yes, 2008
textBy integrating three complementary imaging techniques - ultrasound, elasticity and photoacoustic imaging, a hybrid imaging system utilizing an array transducer is proposed for various biomedical imaging applications including cancer detection ...
Park, Suhyun, 1977-
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Fast Sparse Recovery Algorithm via Resolution Approximation for LASAR 3D Imaging

open access: yesIEEE Access, 2019
Compressed sensing (CS) algorithms are used for linear array synthetic aperture radar (LASAR) three-dimensional (3D) imaging. However, it is difficult to obtain imaging results with both high computational efficiency and promising imaging quality ...
Bokun Tian   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Integrating Motion Compensation With Polar Format Interpolation for Enhanced Highly Squinted Airborne SAR Imagery

open access: yesIEEE Access, 2019
Spatial-variant motion compensation (MOCO) is critical for high resolution and highly squinted airborne synthetic aperture radar (SAR) imaging. Conventional imaging strategies generally perform systematic imaging algorithm and motion compensation ...
Fengfei Wang   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Improved Chirp Scaling Algorithm for Processing Squinted Mode Synthetic Aperture Sonar Data

open access: yesCybernetics and Information Technologies, 2016
The conventional Chirp Scaling Algorithm is mainly used in side looking or small squint angle mode of synthetic aperture imaging. In application of synthetic sonar, the large squint angle imaging is often required and the range-azimuth coupling is ...
Fan Naiqiang, Wang Yingmin, Lv Yarong
doaj   +1 more source

Real-time delay-multiply-and-sum beamforming with coherence factor for in vivo clinical photoacoustic imaging of humans

open access: yesPhotoacoustics, 2019
In the clinical photoacoustic (PA) imaging, ultrasound (US) array transducers are typically used to provide B-mode images in real-time. To form a B-mode image, delay-and-sum (DAS) beamforming algorithm is the most commonly used algorithm because of its ...
Seungwan Jeon   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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