Results 131 to 140 of about 278,031 (168)
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Toward Imaging Biomarkers for Osteoarthritis
Clinical Orthopaedics & Related Research, 2004Many new therapeutic strategies have been and are being developed to correct, prevent, or slow the progression of osteoarthritis. Our ability to evaluate the efficacy of these techniques, or to determine the situations for which they might provide the most benefit, critically depends on diagnostic measures that can serve as proxies for the present or ...
Martha L, Gray +5 more
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Imaging Biomarkers of Spine Osteoarthritis
Current Rheumatology Reviews, 2010While there is an acknowledged need for biomarkers to progress arthritis research, imaging biomarkers for the spine have lagged behind those for peripheral joint osteoarthritis. Progress has been slow for a number of reasons. First and perhaps most importantly, there is currently no international agreement on definition of spine osteoarthritis (OA ...
Maria, Popham, Frances, M K Williams
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Imaging Biomarkers and Imaging Biobanks
2019Several challenges exist for the adoption of advanced image analysis methods in clinical routine. Imaging biomarkers not only have to be objective and reproducible, but they also have to show a clear efficacy in the detection and diagnosis of the disease and/or in the evaluation of treatment response.
Angel Alberich-Bayarri +2 more
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Imaging biomarkers and biotypes for depression
Nature Medicine, 2017A new study identifies four distinct 'biotypes' of depression on the basis of fMRI resting-state functional connectivity in a diverse sample of more than 1,000 individuals. The biotypes are diagnostic of depression and predict treatment response.
Tor D, Wager, Choong-Wan, Woo
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Biomarkers and Imaging of Breast Cancer
American Journal of Roentgenology, 2018The goals of this review are to provide background information on the definitions and applications of the general term "biomarker" and to highlight the specific roles of breast imaging biomarkers in research and clinical breast cancer care. A search was conducted of the main electronic biomedical databases (PubMed, Cochrane, Embase, MEDLINE [Ovid ...
Olena, Weaver, Jessica W T, Leung
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Imaging biomarkers in Parkinson's disease
Progress in Neurobiology, 2011Parkinson's disease (PD) is characterized by a progressive loss of nigrostriatal dopaminergic neurons associated with intracellular Lewy inclusion bodies. The result is poverty of movement, increased muscle rigidity, and tremor at rest and on posture. Midbrain/nigral structural abnormalities can be demonstrated in vivo with both transcranial sonography
Brooks, David J; id_orcid 0000-0003-2602-2518 +1 more
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Genomic and Imaging Biomarkers in Schizophrenia
2018Recent large-scale genomic studies have confirmed that schizophrenia is a polygenic syndrome and have implicated a number of biological pathways in its aetiology. Both common variants individually of small effect and rarer but more penetrant genetic variants have been shown to play a role in the pathogenesis of the disorder.
J T, Reddaway +5 more
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Imaging biomarkers and staging in IPF
Current Opinion in Pulmonary Medicine, 2018The application of computer-based imaging analysis in patients with idiopathic pulmonary fibrosis is a rapidly developing field. The purpose of this review is to provide insights into the problems associated with visual interpretation of HRCT patterns and describe some of the current technologies used to provide objective quantification of disease on ...
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