Results 51 to 60 of about 278,031 (168)
Frontiers in Aging NeuroscienceIntroductionAt least one-third of the identified risk alleles from Genome-Wide Association Studies (GWAS) of Alzheimer’s disease (AD) are involved in lipid metabolism, lipid transport, or direct lipid binding.
Jason Mares +9 more
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Imaging and biomarkers for Alzheimer's disease
Maturitas, 2010 The development of acetyl-cholinesterase inhibitors, and the prospect of future therapies to prevent, or modify, the course of Alzheimer's disease necessitates greater accuracy in diagnosis of this heterogeneous disease. Current diagnosis is based on clinical criteria and neuropathology.
Allan, C +3 more
openaire +3 more sources
Scientific ReportsNasopharyngeal carcinoma (NPC) is notably prevalent in East and Southeast Asia, where despite advancements in radiotherapy leading to high control rates, challenges like radioresistance and collateral tissue damage remain significant. While Schisandrin B
Yanhua Fang +7 more
doaj +1 more source
Imaging biomarker associated with early neurological deterioration in isolated pontine infarction
Frontiers in NeurologyObjectiveTo investigate the association between cerebral small vessel disease burden, along with its individual imaging features, as well as other imaging features and early neurological deterioration in isolated pontine infarction.Methods107 patients ...
Xiaowei Song +8 more
doaj +1 more source
Diagnostics, 2015 Reliable response criteria are critical for the evaluation of therapeutic response in hepatocellular carcinoma (HCC). Current response assessment is mainly based on: (1) changes in size, which is at times unreliable and lag behind the result of therapy ...
Johannes M. Ludwig +4 more
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Toward Imaging Biomarkers for Glycosaminoglycans [PDF]
Journal of Bone and Joint Surgery, 2009 Advances in the diagnosis and treatment of cartilage degeneration will be accelerated with the availability of validated biomarkers that reveal the features relevant to the health of cartilage. Using the delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) technique for evaluating tissue glycosaminoglycan as a case study, I ...
openaire +4 more sources
npj Breast CancerApproximately 80% of all breast cancer cases are estrogen receptor-positive (ER+). This subtype is known to have distant recurrences in a subset of patients after adjuvant endocrine therapy, partially due to the heterogeneity of the disease.
Drashti Jain +10 more
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White paper on imaging biomarkers [PDF]
Insights into Imaging, 2010 Abstract Because of the importance of biomarkers within medicine as a whole and the increasing realisation that imaging can safely provide biomarkers, the ESR executive commissioned this report by experts in the field. It is hoped that further awareness amongst our community will contibute to further exploitation of the enormous wealth of ...
openaire +2 more sources
Association between type 2 diabetes mellitus and body composition based on MRI fat fraction mapping
Frontiers in Public HealthPurposeTo explore the association between type 2 diabetes mellitus (T2DM) and body composition based on magnetic resonance fat fraction (FF) mapping.MethodsA total of 341 subjects, who underwent abdominal MRI examination with FF mapping were enrolled in ...
Qi An +13 more
doaj +1 more source
PET Imaging Biomarkers of Anti-EGFR Immunotherapy in Esophageal Squamous Cell Carcinoma Models
Cells, 2018 Epidermal growth factor receptor (EGFR) is overexpressed and considered as a proper molecular target for diagnosis and targeted therapy of esophageal squamous cell carcinoma (ESCC).
Tae Sup Lee +7 more
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