Results 31 to 40 of about 278,031 (168)

Biomarkers in preclinical cancer imaging [PDF]

European Journal of Nuclear Medicine and Molecular Imaging, 2015
In view of the trend towards personalized treatment strategies for (cancer) patients, there is an increasing need to noninvasively determine individual patient characteristics. Such information enables physicians to administer to patients accurate therapy with appropriate timing.
Bernsen, M.R., Kooiman, K., Segbers, M., Leeuwen, F.W.B. van, Jong, M. de   +4 more
openaire   +4 more sources

Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value

EBioMedicine, 2015
Lung cancer is the most frequent cause of cancer-related death world-wide. Radiotherapy alone or in conjunction with chemotherapy is the standard treatment for locally advanced non-small cell lung cancer (NSCLC).
Michael J. Walker, Cong Zhou, Alison Backen, Maria Pernemalm, Andrew J.K. Williamson, Lynsey J.C. Priest, Pek Koh, Corinne Faivre-Finn, Fiona H. Blackhall, Caroline Dive, Anthony D. Whetton   +10 more
doaj   +1 more source

The Distribution of Major Brain Metabolites in Normal Adults: Short Echo Time Whole-Brain MR Spectroscopic Imaging Findings

Metabolites, 2022
This prospective study aimed to evaluate the variation in magnetic resonance spectroscopic imaging (MRSI)-observed brain metabolite concentrations according to anatomical location, sex, and age, and the relationships among regional metabolite ...
Xinnan Li, Kagari Abiko, Sulaiman Sheriff, Andrew A. Maudsley, Yuta Urushibata, Sinyeob Ahn, Khin Khin Tha   +6 more
doaj   +1 more source

Comparative Sensitivity of MRI Indices for Myelin Assessment in Spinal Cord Regions

Tomography
Background/Objectives: Although multiple magnetic resonance imaging (MRI) indices are known to be sensitive to the noninvasive assessment of myelin integrity, their relative sensitivities have not been directly compared.
Philip Kyeremeh Jnr Oppong, Hiroyuki Hamaguchi, Maho Kitagawa, Nina Patzke, Kevin C. Wakeman, Khin Khin Tha   +5 more
doaj   +1 more source

Detecting Vasodilation as Potential Diagnostic Biomarker in Breast Cancer Using Deep Learning-Driven Thermomics

Biosensors, 2020
Breast cancer is the most common cancer in women. Early diagnosis improves outcome and survival, which is the cornerstone of breast cancer treatment.
Bardia Yousefi, Hamed Akbari, Xavier P.V. Maldague   +2 more
doaj   +1 more source

Imaging Biomarkers for Monitoring the Inflammatory Redox Landscape in the Brain

Antioxidants, 2021
Inflammation is one key process in driving cellular redox homeostasis toward oxidative stress, which perpetuates inflammation. In the brain, this interplay results in a vicious cycle of cell death, the loss of neurons, and leakage of the blood–brain ...
Eduardo Felipe Alves Fernandes, Dennis Özcelik   +1 more
doaj   +1 more source

Imaging biomarkers in multiple sclerosis [PDF]

Journal of Magnetic Resonance Imaging, 2010
AbstractRecent years have witnessed impressive advances in the use of magnetic resonance imaging (MRI) for the assessment of patients with multiple sclerosis (MS). Complementary to the clinical evaluation, conventional MRI provides crucial pieces of information for the diagnosis of MS.
Filippi M, Agosta F
openaire   +3 more sources

Intra-tumoral spatial heterogeneity in breast cancer quantified using high-dimensional protein multiplexing and single cell phenotyping

Breast Cancer Research
Background Breast cancer is a highly heterogeneous disease where variations of biomarker expression may exist between individual foci of a cancer (intra-tumoral heterogeneity).
Alison M. Cheung, Dan Wang, Mary Anne Quintayo, Yulia Yerofeyeva, Melanie Spears, John M. S. Bartlett, Lincoln Stein, Jane Bayani, Martin J. Yaffe   +8 more
doaj   +1 more source

Higher Enhancement Intrahepatic Nodules on the Hepatobiliary Phase of Gd-EOB-DTPA-Enhanced MRI as a Poor Responsive Marker of Anti-PD-1/PD-L1 Monotherapy for Unresectable Hepatocellular Carcinoma

Liver Cancer, 2021
Introduction: Immune checkpoint inhibitors (ICIs) are promising agents for the treatment of hepatocellular carcinoma (HCC). However, the establishment of noninvasive measure that could predict the response to ICIs is challenging.
Tomoko Aoki, Naoshi Nishida, Kazuomi Ueshima, Masahiro Morita, Hirokazu Chishina, Masahiro Takita, Satoru Hagiwara, Hiroshi Ida, Yasunori Minami, Akira Yamada, Keitaro Sofue, Masakatsu Tsurusaki, Masatoshi Kudo   +12 more
doaj   +1 more source

Multiplexed tissue biomarker imaging [PDF]

Journal for ImmunoTherapy of Cancer, 2016
Multiplexed Tissue Biomarker Imaging The detection of structural and functional proteins in cells within the tumor microenvironment in tissue samples is achieved by immunolabeling with specific antibodies.
Stack, Edward C., Foukas, Periklis G., Lee, Peter P.   +2 more
openaire   +4 more sources