Results 11 to 20 of about 278,031 (168)
Imaging Biomarkers in Atherosclerosis Trials [PDF]
Circulation: Cardiovascular Imaging, 2011 Atherosclerosis and its thrombotic complications are the leading cause of morbidity and mortality in developed countries, and the burden of atherosclerotic disease is expected to increase even further in the coming decades due to soaring obesity rates that feed the diabetes epidemic.
Jean-Claude, Tardif +4 more
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Scientific Reports, 2023 T2 lesion quantification plays a crucial role in monitoring disease progression and evaluating treatment response in multiple sclerosis (MS). We developed a 3D, multi-arm U-Net for T2 lesion segmentation, which was trained on a large, multicenter ...
Anitha Priya Krishnan +5 more
doaj +1 more source
Brain Temperature as an Indicator of Cognitive Function in Traumatic Brain Injury Patients
Metabolites, 2023 Whether brain temperature noninvasively extracted by magnetic resonance imaging has a role in identifying brain changes in the later phases of mild to moderate traumatic brain injury (TBI) is not known.
Maho Kitagawa +7 more
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Scientific Reports, 2021 Amyloid plaques are a hallmark of Alzheimer’s disease (AD) that develop in its earliest stages. Thus, non-invasive detection of these plaques would be invaluable for diagnosis and the development and monitoring of treatments, but this remains a challenge
Eugene Kim +10 more
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Imaging Biomarkers in the Clinic [PDF]
Biomarkers in Medicine, 2016 Multimodality medical imaging offers a key role in disease diagnosis, while providing accurate staging and defining disease extent in many instances. Recent developments are increasingly leading to quantitative assessment of medical images, allowing both definition of disease extent, giving insight into the phenotypes of diseases and offering ...
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Alzheimer’s Research & Therapy, 2021 Background The role and implementation of tau PET imaging for predicting subsequent cognitive decline in Alzheimer’s disease (AD) remains uncertain. This study was designed to evaluate the relationship between baseline [18F]GTP1 tau PET and subsequent ...
Edmond Teng +8 more
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Applications of Click Chemistry in Radiopharmaceutical Development
CHIMIA, 2010 Click chemistry, a concept that employs only practical and reliable transformations for compound synthesis, has made a significant impact in several areas of chemistry, including material sciences and drug discovery.
Joseph C. Walsh, Hartmuth C. Kolb
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MRI Volumetric Analysis of the Thalamus and Hypothalamus in Amyotrophic Lateral Sclerosis
Frontiers in Aging Neuroscience, 2022 Background: Increasing evidence has shown that amyotrophic lateral sclerosis (ALS) can result in abnormal energy metabolism and sleep disorders, even before motor dysfunction.
Shan Ye +17 more
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Integration of Biomarkers and Imaging [PDF]
Journal of Thoracic Oncology, 2006 Imaging studies provide essential diagnostic information in the care of cancer patients. Unfortunately, radiographic findings are not always diagnostic and thus an alternative approach with biomarkers has been suggested as part of the diagnostic evaluation. This discussion focuses on integration of biomarkers with imaging in the effort to guide patient
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Frontiers in Immunology, 2020 The development and progression of solid tumors such as colorectal cancer (CRC) are known to be affected by the immune system and cell types such as T cells, natural killer (NK) cells, and natural killer T (NKT) cells are emerging as interesting targets ...
Natalie Zwing +9 more
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