Results 101 to 110 of about 6,084,382 (354)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

A novel multi-modality imaging phantom for validating interstitial needle guidance for high dose rate gynecological brachytherapy. [PDF]

open access: yesJ Appl Clin Med Phys, 2023
Eckroate B   +9 more
europepmc   +1 more source

Tissue-mimicking phantoms for photoacoustic and ultrasonic imaging

open access: yesBiomedical Optics Express, 2011
In both photoacoustic (PA) and ultrasonic (US) imaging, overall image quality is influenced by the optical and acoustical properties of the medium. Consequently, with the increased use of combined PA and US (PAUS) imaging in preclinical and clinical applications, the ability to provide phantoms that are capable of mimicking desired properties of soft ...
Jason R. Cook   +2 more
openaire   +3 more sources

NEMA image quality phantom measurements and attenuation correction in integrated PET/MR hybrid imaging

open access: yesEJNMMI Physics, 2015
BackgroundIn integrated PET/MR hybrid imaging the evaluation of PET performance characteristics according to the NEMA standard NU 2–2007 is challenging because of incomplete MR-based attenuation correction (AC) for phantom imaging.
S. Ziegler   +4 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Fabrication of a spherical inclusion phantom for validation of magnetic resonance-based magnetic susceptibility imaging.

open access: yesPLoS ONE, 2019
Fabrication of a spherical multi-compartment MRI phantom is demonstrated that can be used to validate magnetic resonance (MR)-based susceptibility imaging reconstruction.
Jun-Ho Kim   +4 more
doaj   +1 more source

A patient-specific multi-modality abdominal aortic aneurysm imaging phantom. [PDF]

open access: yesInt J Comput Assist Radiol Surg, 2022
Little CD   +10 more
europepmc   +1 more source

Seeing the phantom: A functional magnetic resonance imaging study of a supernumerary phantom limb

open access: yesAnnals of Neurology, 2009
AbstractObjectiveSupernumerary phantom limb (SPL) is a rare neurological manifestation where patients with a severe stroke‐induced sensorimotor deficit experience the illusory presence of an extra limb that duplicates a real one. The illusion is most often experienced as a somesthetic phantom, but rarer SPLs may be intentionally triggered or seen. Here,
Alan J. Pegna   +9 more
openaire   +5 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom. [PDF]

open access: yesTomography, 2023
Malyarenko D   +14 more
europepmc   +1 more source

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