Results 131 to 140 of about 6,210,221 (335)

Performance evaluation of a novel brain-dedicated SPECT system

EJNMMI Physics, 2018
Background Single-photon emission computed tomography (SPECT) imaging is an important diagnostic tool for the early detection of the loss of nigrostriatal dopaminergic neurons in Parkinson’s disease (PD) and similar neurodegenerative disorders ...
M. K. Stam, E. E. Verwer, J. Booij, S. M. Adriaanse, C. M. de Bruin, T. C. de Wit   +5 more
doaj   +1 more source

Influence of beam hardening in dual-energy CT imaging: phantom study for iodine mapping, virtual monoenergetic imaging, and virtual non-contrast imaging. [PDF]

Eur Radiol Exp, 2021
Kanatani R, Shirasaka T, Kojima T, Kato T, Kawakubo M.   +4 more
europepmc   +1 more source

How local is the Phantom Force? [PDF]

arXiv, 2012
The phantom force is an apparently repulsive force, which can dominate the atomic contrast of an AFM image when a tunneling current is present. We described this effect with a simple resistive model, in which the tunneling current causes a voltage drop at the sample area underneath the probe tip.
arxiv  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Application value of contrast‐enhanced ultrasound in preoperative localization of microwave ablation for primary hyperparathyroidism

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background Ultrasonography (US) and 99mTechnetium‐sestamibi scintigraphy (99mTc‐MIBI) are currently first‐line imaging modalities to localize parathyroid adenomas with sensitivities of 80% and 84%, respectively. Therefore, finding other modalities to further improve the diagnostic accuracy for preoperative localization is critically needed ...
Fangyi Liu, Li Zang, Yunlin Li, Zhiwei Guan, Yang Liu, Xiaoling Yu, Zhiyu Han, Ping Liang   +7 more
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Statistical process control to monitor use of a web‐based autoplanning tool

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the use of statistical process control (SPC) for quality assurance of an integrated web‐based autoplanning tool, Radiation Planning Assistant (RPA). Methods Automatically generated plans were downloaded and imported into two treatment planning systems (TPSs), RayStation and Eclipse, in which they were recalculated using ...
Hunter Mehrens, Raphael Douglas, Mary Gronberg, Kelly Nealon, Joy Zhang, Laurence Court   +5 more
wiley   +1 more source

3D printed human skull phantoms for transcranial photoacoustic imaging [PDF]

arXiv
Photoacoustic (PA) waves are strongly distorted and attenuated in skull bone. To study these effects on PA imaging, we designed and 3D-printed tissue-mimicking phantoms of human skull. We present a comparison of results in phantom and ex vivo skull.
arxiv  

Machine learning for automatic construction of pseudo-realistic pediatric abdominal phantoms [PDF]

arXiv, 2019
Machine Learning (ML) is proving extremely beneficial in many healthcare applications. In pediatric oncology, retrospective studies that investigate the relationship between treatment and late adverse effects still rely on simple heuristics. To assess the effects of radiation therapy, treatment plans are typically simulated on phantoms, i.e., virtual ...
arxiv  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source