Results 181 to 190 of about 1,882,249 (253)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

CT texture phantom dataset with paired image quality assessments for quantitative imaging. [PDF]

Med Phys
Daly MA, Hoffman JM, Hernandez AM, Uneri A, Varghese BA, Levy J, McNitt-Gray MF.   +6 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Obese patient imaging: Potential dose reduction with photon-counting CT. [PDF]

J Appl Clin Med Phys
Liu LP, Mei K, Sharma S, Ross S, Halliburton SS, Thompson R, Akino N, Dhanaliwala AH, Roshkovan L, Litt HI, Noël PB.   +10 more
europepmc   +1 more source

Biologically relevant photoacoustic imaging phantoms with tunable optical and acoustic properties. [PDF]

J Biomed Opt, 2016
Vogt WC, Jia C, Wear KA, Garra BS, Joshua Pfefer T.   +4 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Investigation of High Pulse Repetition Frequency Single-Cycle Histotripsy for Rapid Tissue Ablation. [PDF]

Ultrasound Med Biol
Simon A, Ruger L, Vickers E, Holmes L, Paul T, Macco A, Coutermarsh-Ott S, Maxwell A, Vlaisavljevich E.   +8 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

OpenQPAIData: Measurements of test objects with reference labels for quantitative photoacoustic imaging research. [PDF]

Sci Data
Gröhl J, Kalva SK, Lafci B, Di Cecio F, Tao R, Else TR, Wright L, Razansky D, Bohndiek SE.   +8 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source