From fatal disease to functional cure: 25 years of tyrosine kinase inhibition in chronic myeloid leukemia. [PDF]
Hochhaus A +9 more
europepmc +1 more source
ABSTRACT Objective To investigate the development of oral premalignant and malignant lesions as a major long‐term complication following hematopoietic stem cell transplantation. Methods This single‐center retrospective study identified 17 patients who developed 26 pathology‐confirmed oral premalignant and malignant lesions after hematopoietic stem cell
Pei Hsuan Lu +3 more
wiley +1 more source
First case report of hypouricemia associated with adjuvant imatinib therapy in a patient with small intestinal gastrointestinal stromal tumor. [PDF]
Bu J +4 more
europepmc +1 more source
A scoping review of imatinib-induced testicular toxicity and male fertility impairment. [PDF]
Ji X +4 more
europepmc +1 more source
A comprehensive analysis of the adverse drug events of metastatic and unresectable gastrointestinal stromal tumor treatment options: avapritinib, imatinib, regorafenib, ripretinib, and sunitinib safety insights and implications. [PDF]
Thompson CM, Andrews MB, Adler DG.
europepmc +1 more source
Effects of the novel aurora kinase/JAK inhibitor, AT9283 and imatinib on Philadelphia positive cells in vitro [PDF]
Lyons, John +4 more
core +1 more source
Characterizing P-glycoprotein and Breast Cancer Resistance Protein interactions of asciminib among other tyrosine kinase inhibitors used in chronic myeloid leukemia. [PDF]
Verhagen NE +7 more
europepmc +1 more source
ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu +8 more
wiley +1 more source
Roles of extracellular vesicles in the pathogenesis of chronic myeloid leukemia. [PDF]
Hrdinova T, Kupcova Skalnikova H.
europepmc +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source

