Results 151 to 160 of about 72,525 (247)

Cumulative clinical experience from a decade of use: imatinib as first-line treatment of chronic myeloid leukemia

, 2012
Yusuf Baran,1 Guray Saydam21Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Turkey; 2Department of Hematology, School of Medicine, Ege University, Izmir, TurkeyAbstract: Chronic myeloid leukemia (CML) is a malignant ...
Saydam G, Baran Y
core  

Therapeutic drug-monitoring-guided desensitization for severe imatinib-associated rash. [PDF]

J Gastrointest Oncol
Dy PS, Lou E.
europepmc   +1 more source

Dissecting Bone Marrow Fibrosis in Philadelphia‐Negative Myeloproliferative Neoplasms: Multiple Roads Lead to Rome

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT Philadelphia‐negative myeloproliferative neoplasms (MPN), a spectrum of blood malignancies characterized by uncontrolled myeloid proliferation, persist as a key challenge in onco‐hematology due to their intricate molecular background, heterogeneous clinical phenotypes, and variable prognoses.
Mariagiovanna Ballato, Vincenzo Fiorentino, Gabriele Ricciardi, Pietro Tralongo, Emanuela Germanà, Alessandro Allegra, Fabio Stagno, Guido Fadda, Maurizio Martini   +8 more
wiley   +1 more source

Imatinib as the first and only treatment in Europe for adult patients at significant risk of relapse following gastrointestinal stromal tumor removal

, 2010
F Duffaud, S Salas, T Huyn, JL DevilleLa Timone University Hospital, Marseille, FranceAbstract: Mutations of the KIT gene are the molecular hallmark of most gastrointestinal stromal tumors (GISTs).
F Duffaud, T Huyn, et al, S Salas
core  

Volumetric Microsampling for Patient‐Centric Therapeutic Drug Monitoring in Clinical Pharmacology: A Scoping Review

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala, Abbie D. Leino, Nathaniel J. Rhodes, Kevin J. Downes, Marc H. Scheetz, Manjunath P. Pai   +5 more
wiley   +1 more source

Imatinib-Induced Changes in Anxiety-Like Behaviors are Associated With Prefrontal Cortical Metabolic Remodeling in Mice. [PDF]

Alpha Psychiatry
Ji J, Wang Y, Qu S, Peng X, Ma R, Li H, Chang J, Li L, Li Y, Gong Z.   +9 more
europepmc   +1 more source

Performance of Survival Prediction Tools in Patients With Gastrointestinal Stromal Tumors: A Systematic Review and Meta‐Analysis

Journal of Surgical Oncology, Volume 134, Issue 3, Page 359-382, September 2026.
ABSTRACT Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. We conducted a systematic review and meta‐analysis of studies that developed, validated, or updated clinical prognostic tools to predict survival in adults with primary GIST, identifying 47 eligible studies (38 development and 9 ...
Alice Zhu, Chloe Wong, Neill K. J. Adhikari, Ka Yan Ip, Alyson Mahar, Amy T. Hsu, Julie Hallet, Natalie Coburn   +7 more
wiley   +1 more source

Clinical Validity of Imatinib Therapeutic Drug Monitoring in a Real-World Italian Cohort of Gastrointestinal Stromal Tumors and the Role of Patients' Sex. [PDF]

Pharmaceutics
Gagno S, Buonadonna A, Cecchin E, Fumagalli A, Posocco B, Canil G, Cecchin R, Guardascione M, Montico M, Puglisi F, Cecchin E.   +10 more
europepmc   +1 more source

Current Evidence for Circulating Tumor DNA in Sarcoma: Challenges and Opportunities for Clinical Application

Journal of Surgical Oncology, Volume 134, Issue 4, Page 490-501, September 15, 2026.
ABSTRACT Sarcomas represent a diverse group of mesenchymal tumors with high rates of recurrence after resection. While recent technical advances have enabled the detection of rare circulating tumor DNA (ctDNA) in other malignancies, the complexity and heterogeneity of sarcoma genomics have historically limited ctDNA in these cancers.
Kristin E. Goodsell, Jason A. Carter, Hannah R. Abrams, Harveshp Mogal, Elizabeth T. Loggers, Jeremy Sharib   +5 more
wiley   +1 more source

Primary Peritoneal Perivesical Hemangiosarcoma in 16 Dogs (2020–2024)

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Primary peritoneal perivesical hemangiosarcoma in dogs may represent a distinct anatomical presentation of visceral hemangiosarcoma. Despite a high metastatic rate and guarded prognosis, multimodal treatment combining surgery and chemotherapy significantly improved progression‐free and disease‐specific survival compared with chemotherapy alone ...
Jose Roca, Xavier Escoda, Miguel García‐de la Virgen, Ignasi Rodríguez   +3 more
wiley   +1 more source