Results 161 to 170 of about 106,545 (283)

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

Imatinib mesylate (STI571) therapy for Philadelphia chromosome–positive chronic myelogenous leukemia in blast phase

, 2002
Hagop M. Kantarjian, Jorge E. Cortés, Susan O’Brien, Francis J. Giles, Maher Albitar, Mary Beth Rios, Jianqin Shan, Stefan Faderl, Guillermo Garcia‐Manero, Deborah A. Thomas, Debra Resta, Moshe Talpaz   +11 more
openalex   +1 more source

Imatinib administration in two patients with liver metastases from GIST and severe jaundice [PDF]

, 2003
Tommaso De Pas, Romano Danesi, Chiara Catania, Giuseppe Curigliano, Filippo de Braud   +4 more
openalex   +1 more source

Chronic myeloid leukemia outcomes according to baseline risk and first‐line treatment in real‐world settings: Data from the Italian Network/CML Campus

Cancer, Volume 131, Issue 13, 1 July 2025.
Abstract Background Improved outcome has been reported in chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs) in sponsored trials. Methods This is a multicenter prospective cohort study of consecutive patients with newly diagnosed chronic phase CML from 19 regions in Italy.
Valentina Giai, Tiziana Rosso, Fausto Castagnetti, Patrizia Pregno, Massimiliano Bonifacio, Isabella Capodanno, Mario Tiribelli, Fabio Stagno, Giovanni Caocci, Antonella Gozzini, Luigiana Luciano, Sara Galimberti, Monica Bocchia, Andrea Patriarca, Giuseppe Lanzarone, Bruno Martino, Anna Guella, Anna Rita Scortechini, Carmen Fava, Claudio Fozza, Simona Sica, Nicola Di Renzo, Pellegrino Musto, Domenico Pastore, Alessandro Maggi, Michele Pizzuti, Lorella Maria Antonia Melillo, Angelo Michele Carella, Giuseppe Tarantini, Anna Mele, Elisabetta Calistri, Maria Rosaria Coppi, Fabio Saccona, Emilia Scalzulli, Beatrice Battaglio, Miriam Iezza, Cinzia Bitetti, Roberto Freilone, Gianantonio Rosti, Francesco Albano, Fabrizio Pane, Giorgina Specchia, Giovannino Ciccone, Giuseppe Saglio, Massimo Breccia   +44 more
wiley   +1 more source

The effectiveness and cost-effectiveness of imatinib in chronic myeloid leukaemia: a systematic review

, 2002
Ruth Garside, A Round, Kim Dalziel, Ken Stein, Pamela Royle   +4 more
openalex   +1 more source

Is there a cloud in the silver lining for imatinib? [PDF]

, 2003
Sarah Paterson, Kevin D. Smith, Tessa L. Holyoake, Heather G. Jørgensen   +3 more
openalex   +1 more source

Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT A 21‐year‐old miniature donkey gelding was evaluated for pruritus, inappetence, hypertriglyceridemia, and alopecia of 2 weeks' duration. Hematology showed moderate eosinophilia, severe hypertriglyceridemia, and moderately increased liver enzyme activities. Cytologic evaluation of peritoneal fluid identified an eosinophilic transudate.
Carla K. Enriquez, Alicia E. Long, Cristobal Navas de Solis, Perry L. Habecker, Rose Nolen‐Walston   +4 more
wiley   +1 more source

CNS and Cutaneous Involvement in Patients With Chronic Myeloid Leukemia Treated With Imatinib in Hematologic Complete Remission: Two Case Reports [PDF]

, 2003
Elisabetta Abruzzese, Maria Cantonetti, Luciana Morino, G Orlandi, Andrea Tendas, Maria Ilaria Del Principe, M Masi, Sergio Amadori, Augusto Orlandi, Lucia Anemona, Elena Campione   +10 more
openalex   +1 more source

Imatinib in breast milk [PDF]

Annals of Hematology, 2009
Kronenberger, Roland, Schleyer, Eberhard, Bornhäuser, Martin, Ehninger, Gerhard, Gattermann, Norbert, Blum, Sabine   +5 more
openaire   +3 more sources

Recent Green and Sustainable Pd‐Catalyzed Aminations

ChemSusChem, Volume 18, Issue 12, June 17, 2025.
Herein, several sustainable methods toward Pd‐catalyzed aminations of aryl/heteroaryl (pseudo)halides with alkyl and (hetero)aryl amines are discussed. The use of bio‐derived solvents or recyclable aqueous micellar media allows for reduced Pd loadings without using egregious organic solvents.
John Michael Saunders, Kylee B. Dismuke Rodriguez, Robert M. Lammert, Jordan R. Yirak, Karthik S. Iyer, Madison J. Wong, Bruce H. Lipshutz   +6 more
wiley   +1 more source