Results 61 to 70 of about 12,515 (211)
Ankle arthroscopy is characterized by its short duration, minimal trauma, and rapid recovery. Moreover, it enables clear visualization of lesions, and with the use of multiportal approaches, complete excision of diffuse‐type tenosynovial giant cell tumors (Dt‐TGCTs) within the ankle joint cavity is feasible.
Jiayao Zhang+9 more
wiley +1 more source
Platelet Dysfunction in Patients with Chronic Myeloid Leukemia: Does Imatinib Mesylate Improve It?
INTRODUCTION: The aim of this study was to investigate the effects of imatinib mesylate on platelet aggregation and adenosine triphosphate (ATP) release in chronic myeloid leukemia patients. METHODS: Platelet aggregation and ATP release induced by 5.0 mM
Olga Meltem Akay+2 more
doaj +1 more source
Abstract Background Gastrointestinal stromal tumors (GISTs) are clinically heterogeneous with various malignant potential in different individuals. It is crucial to explore a reliable method for preoperative risk stratification of gastric GISTs noninvasively.
Ping Yang+5 more
wiley +1 more source
Imatinib mesylate, showed encouraging activity in chronic myelogenous leukemia. However, there are few data regarding his efficacy and response monitoring in Sub-Saharan African patients. Our objective was to assess response to imatinib mesylate (Glivec)
K. G. Koffi+13 more
doaj +1 more source
A two-year-old spayed female American shorthair cat presented with a rough, circular, exophytic mass on the genital area. The clinical findings and histopathological examination revealed that the mass contained neoplastic mast cells and, thus, was ...
Joonyoung Kim, Ha-Jung Kim
doaj +1 more source
We report an atypical case of Wells syndrome in conjunction with rare eosinophilic disorders such as hypereosinophilic syndrome and eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome). Abstract Eosinophilic cellulitis or Wells syndrome encompasses distinct histopathological features but can also be associated with eosinophilic ...
Domniki Iatropoulou+4 more
wiley +1 more source
In this report, a lentivirus‐based reporter cell system using a highly sensitive YAP1/TAZ/TEAD‐responsive DNA element was established. This system provides a versatile tool for assessing the endogenous YAP1/TAZ activity and exploring their novel modulators. Abstract The activation of yes‐associated protein 1 (YAP1) and transcriptional co‐activator with
Hiroki Hikasa+11 more
wiley +1 more source
Serious Skin Reaction Associated with Imatinib in a Patient with Chronic Myeloid Leukemia
Imatinib mesylate (STI 571) is one of the fundamental chemotherapeutic agents used in the treatment of the chronic, accelerated and blastic phases of chronic myelocytic leukemia (CML), gastrointestinal stromal tumors and Philadelphia chromosome–positive ...
Murat Albayrak+6 more
doaj
Imatinib mesylate is a tyrosine kinase inhibitor of c-KIT and PDGFRA. Imatinib mesylate is an effective drug that can be used as a first-choice agent for treatment of GISTs. Prior to treatment, molecular diagnosis of c-KIT or PDGFRA is necessary; however,
Kazunori Otsuka+10 more
doaj +1 more source
Background Imatinib mesylate is the first line treatment for chronic myeloid leukemia. In patients with advanced phase of the disease, the advent of imatinib significantly increased survival.
Francesca Palandri+21 more
doaj +1 more source