Results 71 to 80 of about 26,042 (243)

Effects of Static and Low‐Frequency Magnetic Fields on Gene Expression

open access: yesJournal of Magnetic Resonance Imaging, Volume 62, Issue 2, Page 317-334, August 2025.
Substantial research over the past two decades has established that magnetic fields affect fundamental cellular processes, including gene expression. However, since biological cells and subcellular components exhibit diamagnetic behavior and are therefore subjected to very small magnetic forces that cannot directly compete with the viscoelastic and ...
Vitalii Zablotskii   +3 more
wiley   +1 more source

Imatinib resistance: diagnostic and therapeutic choices

open access: yesClinical Management Issues, 2015
We report a case of a 42-year-old woman with t(9;22) positive chronic myeloid leukemia (CML) who developed a sub-optimal response to therapy with imatinib mesylate due to M351T mutation and low plasma level of imatinib. Dose increase of imatinib resulted
Marianna De Muro   +3 more
doaj   +1 more source

Hyaluronic Acid‐Decorated Liposomes for the Intrapulmonary Delivery of Imatinib: A Targeted Treatment for Postinflammatory Pulmonary Fibrosis

open access: yesSmall Science, Volume 5, Issue 8, August 2025.
Hyaluronic acid‐decorated imatinib‐loaded liposomes are developed to specific target CD44 receptor expressed by interstitial lung fibrosis cells, demonstrating higher uptake than empty liposomes. Based on promising in vitro data, they are administered intratracheally and intraperitoneally in a mouse bleomycin model, assessing their ability to decrease ...
Sara Bozzini   +13 more
wiley   +1 more source

Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS [PDF]

open access: yes, 2011
The LC-ESI-MS was developed and validated for the analysis of imatinib in plasma and bone marrow samples using deuterated imatinib (D(8)-IM) as an internal standard. The biological samples were extracted using Strata-X-C SPE cartridges and separated on C&
Elliott, M.   +4 more
core   +1 more source

Imatinib-mesylate for all patients with hypereosinophilic syndrome? [PDF]

open access: yes, 2004
Some recent papers have focused on the activity of imatinib-mesylate, a selective inhibitor of tyrosine kinase, in idiopathic hypereosinophilic syndrome (HES) [1], [2], [3] and [4].
Carella, A   +5 more
core   +1 more source

Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT A 21‐year‐old miniature donkey gelding was evaluated for pruritus, inappetence, hypertriglyceridemia, and alopecia of 2 weeks' duration. Hematology showed moderate eosinophilia, severe hypertriglyceridemia, and moderately increased liver enzyme activities. Cytologic evaluation of peritoneal fluid identified an eosinophilic transudate.
Carla K. Enriquez   +4 more
wiley   +1 more source

XML Evaluation of Thyroid Dysfunction during Imatinib Therapy in Chronic Myeloid Leukemia

open access: yesIranian Journal of Blood and Cancer, 2016
Background: Imatinib mesylate is the first generation of Tyrosine kinase inhibitors (TKI) and highly effective in the treatment of chronic myeloid leukemia (CML).
Abolghasem Allahyari   +3 more
doaj  

Imatinib and hypophosphatemia: Case report and review of literature

open access: yesJournal of Oncological Sciences, 2017
Imatinib mesylate is a potent inhibitor of the BCR-Abl kinases, c-Kit, PDGFR, and fms. Imatinib used for treatment of chronic myeloid leukemia and gastrointestinal stromal tumor. Imatinib has been well tolerated.
Erdem Şen, İrem Öner, Özlem Ata
doaj   +1 more source

V559A and N822I double KIT mutant melanoma with predictable response to imatinib? [PDF]

open access: yes, 2011
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/88125/1/j.1755-148X.2010.00822.x ...
Betz, Bryan   +3 more
core   +1 more source

The teratogenic effects of imatinib mesylate on rat fetuses

open access: yesToxicology Reports, 2015
Imatinib mesylate, a selective tyrosine kinase inhibitor, is the first line treatment against chronic myelogenous leukemia and gastrointestinal stromal tumors.
M.M. El Gendy   +3 more
doaj   +1 more source

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