Results 71 to 80 of about 222,810 (285)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Noise-Aware Undersampling for imbalanced medical data (NAUS)

open access: yesInformatics in Medicine Unlocked
Advancements in medical research have increasingly relied on robust data analytics to support diagnostic and treatment decisions. However, data analysis still faces challenges when investigating datasets with severe class imbalance, often stemming from ...
Zholdas Buribayev   +3 more
doaj   +1 more source

Oversampling for Imbalanced Learning Based on K-Means and SMOTE

open access: yes, 2017
Learning from class-imbalanced data continues to be a common and challenging problem in supervised learning as standard classification algorithms are designed to handle balanced class distributions. While different strategies exist to tackle this problem,
Bacao, Fernando   +2 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Predictive Analytics Data Mining in Imbalanced Medical Dataset

open access: yesJurnal Komputer Terapan, 2016
Predictive Analytics Data Mining in Imbalanced Medical ...
Dini Hidayatul Qudsi
doaj  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

DPC-SMOTE Over-sampling Algorithm for Imbalanced Data Classification

open access: yesJournal of Harbin University of Science and Technology
An oversampling algorithm based on density peak clustering is proposed to solve the problem of noise and imbalance among classes in imbalanced data sets.
LIU Zhihan, ZHANG Zhonglin, ZHAO Lei
doaj   +1 more source

A Classification Method Based on Feature Selection for Imbalanced Data

open access: yesIEEE Access, 2019
Imbalanced data are very common in the real world, and it may deteriorate the performance of the conventional classification algorithms. In order to resolve the imbalanced classification problems, we propose an ensemble classification method that ...
Yi Liu   +4 more
doaj   +1 more source

Visual-Based Analysis of Classification Measures with Applications to Imbalanced Data

open access: yes, 2017
With a plethora of available classification performance measures, choosing the right metric for the right task requires careful thought. To make this decision in an informed manner, one should study and compare general properties of candidate measures ...
Brzezinski, Dariusz   +3 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

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