Results 141 to 150 of about 40,836 (345)

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Advanced Multiscale Modeling for Revealing Anomalous Fluid Transport Induced by Confinement Interfacial Layer Reconstruction in Sub‐10 nm Space

Advanced Science, EarlyView.
Integrating experimental insights with molecular dynamics simulations, we establish an advanced mathematical model for fluids confined in sub‐10‐nm channels, enabling quantitative prediction of interfacial layer thickness and viscosity by accounting for channel material, temperature, and fluid properties.
Xiang Zhang, Bing Wei, Jingyi Wang, Runnan Wu   +3 more
wiley   +1 more source

Effect of dynamic displacement and imbibition on oil recovery in tight oil reservoirs: pore-scale simulation

Journal of Petroleum Exploration and Production Technology
Tight oil reservoirs are widely treated as a promising alternative for future hydrocarbon extraction due to their large reserves and high development potential.
Cong Li, Daigang Wang, Jingjing Sun, Yao Zhao, Fangzhou Liu, Jin Chen   +5 more
doaj   +1 more source

Experimental Investigation of Factors Influencing Spontaneous Imbibition in Shale Reservoirs

The flowback rate of fracturing fluid in shale reservoirs is often notably low, primarily due to the spontaneous imbibition of the water-based fracturing fluid.
Mingjun Chen, Li Liu, Wen-Xin Yang, Ya-Wan Tang, Shuqiang Shi, Ji-Qing Li, Yi-Min Wang, Qian Zhang, Ai-Wei Zheng   +8 more
core   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

A systematic research on spontaneous imbibition of surfactant solutions for low permeability sandstone reservoirs

, 2021
Derong Xu, Zhe Li, B. Bai, Xin Chen, Hairong Wu, J. Hou, Wanli Kang   +6 more
semanticscholar   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Cobalt Single‐Atom Catalysts for Ultrafast Sulfamethoxazole Degradation: Unveiling the Chloride‐Ion‐Enhanced Formation of Co(IV)=O

Advanced Science, EarlyView.
An atomically dispersed Co–N4 single‐atom catalyst rapidly activates peroxymonosulfate to remove the antibiotic sulfamethoxazole from water. Common ions have little impact, but chloride dramatically speeds degradation by promoting a high‐valent Co(IV) = O oxidant via in situ HOCl–catalyst electron transfer.
Anting Ding, Jing Lu, Yafei Fan, Chenyu Zeng, Yuhang Lin, Yufei Shi, Zulin Zhang   +6 more
wiley   +1 more source

Experimental Study on the Mechanism of Enhanced Imbibition with Different Types of Surfactants in Low-Permeability Glutenite Reservoirs

Molecules
Due to the complex physical properties of low-permeability glutenite reservoirs, the oil recovery rate with conventional development is low. Surfactants are effective additives for enhanced oil recovery (EOR) due to their good ability of wettability ...
Hongyan Qu, Jilong Shi, Mengyao Wu, Fujian Zhou, Jun Zhang, Yan Peng, Tianxi Yu, Zhejun Pan   +7 more
doaj   +1 more source