Results 81 to 90 of about 230,890 (239)

CD14 plays a critical role in pain and inflammation across multiple models of post‐traumatic osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine OA models that vary in severity of pathology and rate of progression, to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt   +18 more
wiley   +1 more source

Quality indicators for safe and effective medication use in long‐term care facilities: A modified Delphi study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This modified Delphi study aimed to achieve expert agreement on quality indicators (QIs) suitable for application at the population level, to evaluate quality use of medications and pharmacist services in long‐term care facilities (LTCFs). Methods We conducted a two‐round modified online Delphi study with a multidisciplinary panel of Australian ...
Daria S. Gutteridge   +10 more
wiley   +1 more source

Mimicking The Photosynthetic Special Pair With Aluminum(III) Porphyrin Homodimer – Fullerene (C60) Supramolecular Assemblies Capable of Long‐Lived Charge Separation

open access: yesChemistry – A European Journal, EarlyView.
The axial‐bonding of aluminum(III) porphyrins was used to create two covalently linked special‐pair mimics to probe charge‐transfer between a porphyrin dimer and a C60 unit for artificial photosynthesis. Although excitonic coupling between the porphyrins is weak, incorporation of a second porphyrin markedly increases both the yield and lifetime of the ...
Stefan Charon   +7 more
wiley   +1 more source

Adaptive internal model control design for positioning control of a piezo-ceramic actuator with rate-dependent hysteresis

open access: yesMechanical Engineering Journal, 2015
This paper proposes the novel design of a positioning control system of a piezo-ceramic actuator. Piezo-ceramic actuators have been used extensively in many engineering applications which require high precision positioning. However, it is well known that
Dongbo LIU, Fumitake FUJII
doaj   +1 more source

Vibrational properties of inclusion complexes: the case of indomethacin-cyclodextrin

open access: yes, 2006
Vibrational properties of inclusion complexes with cyclodextrins are studied by means of Raman spectroscopy and numerical simulation. In particular, Raman spectra of the non-steroidal, anti-inflammatory drug indomethacin undergo notable changes in the ...
Anderson A.   +8 more
core   +1 more source

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo   +8 more
wiley   +1 more source

Modelling Sustainability Performance in Manufacturing Companies

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Nowadays, organisations need to operate with economic, social and environmental goals in mind. Indices objectively quantify such goals; hence, an organisation can develop and compare policies based on future index values. We propose a system dynamics‐based model of a manufacturing company that frames its operations in terms of a set of easily ...
Harol Andrey Avila‐Choconta   +3 more
wiley   +1 more source

Barriers to the implementation of Integrated Marketing Communications: the client perspective [PDF]

open access: yes, 2012
Discussions on Integrated Marketing Communications (IMC) in the academic and practitioner journals are gradually changing from examining definitions and justifications to sharing good practice, with an acceptance that IMC is the only way forward in the ...
Laurie, Sally, Mortimer, Kathleen
core  

Reachability in Parametric Interval Markov Chains using Constraints

open access: yes, 2017
Parametric Interval Markov Chains (pIMCs) are a specification formalism that extend Markov Chains (MCs) and Interval Markov Chains (IMCs) by taking into account imprecision in the transition probability values: transitions in pIMCs are labeled with ...
A Puggelli   +13 more
core   +3 more sources

A Computational Workflow for Cell Line Profiling by Imaging Mass Cytometry

open access: yesCytometry Part A, EarlyView.
ABSTRACT In single‐cell spatial phenotyping biology, imaging mass cytometry (IMC) stands out as a cutting‐edge, highly multiplexed technology driving discoveries across various disease areas. In vitro profiling relies on tumor‐derived cancer cell lines, known for their diverse morphologies and phenotypes.
Alexandre Bouzekri   +2 more
wiley   +1 more source

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