Results 31 to 40 of about 378 (110)

Multicentric Castleman disease presenting with orbital involvement progressing to TAFRO syndrome: a case report. [PDF]

BMC Ophthalmol
Background Castleman Disease (CD) can be unicentric or multicentric, with the ocular involvement rare; notably, the aggressive TAFRO syndrome (TS) is a subtype of idiopathic multicentric CD (iMCD). Ocular involvement in CD is rare, and to date, there are
Wei Y, Qi J, Yan J, Gao G, Ji X, Yu D, Chen W, Huang D.   +7 more
europepmc   +2 more sources

Epstein–Barr Virus-Positive Cutaneous and Systemic Plasmacytosis with TAFRO Syndrome-like Symptoms Successfully Treated with Rituximab

Medicina, 2023
Histopathologic findings in the lymph nodes of patients with thrombocytopenia, anasarca, fever, reticulin fibrosis, renal dysfunction, and organomegaly (TAFRO) syndrome are similar to those of idiopathic multicentric Castleman’s disease (iMCD), but TAFRO
Seiji Kakiuchi, Hiroaki Akiyama, Isamu Harima, Ikumi Takagi, Junpei Rikitake, Yoko Kozuki, Mayumi Inaba, Hiroshi Fujiwara, Nozomu Kurose, Sohsuke Yamada, Yasufumi Masaki   +10 more
doaj   +1 more source

Idiopathic multicentric Castleman disease with positive antiphospholipid antibody: atypical and undiagnosed autoimmune disease? [PDF]

, 2022
Idiopathic multicentric Castleman disease (iMCD) is a systemic disorder characterized by systemic inflammation and organ dysfunction associated with an increase in pro-inflammatory cytokines.
Czech, Torrey, Mizuno, Hiroki, Momose, Shuji, Nishikori, Asami, Nishimura, Midori Filiz, Nishimura, Yoshito, Ohsawa, Kumiko, Otsuka, Fumio, Otsuka, Yuki, Sato, Yasuharu, Sawa, Naoki, Sawada, Haruki   +11 more
core   +1 more source

Multicentric vs. Unresectable Unicentric Castleman Disease with Active Presentation: An Orphan Rare Disease in a Young Egyptian Female Patient. A Case Report [PDF]

Research in Oncology, 2023
Background: Castleman disease (CD) is a rare disorder that affects lymph nodes and has a wide range of associated symptoms. The affected lymph nodes show characteristic histological picture.
Yasmine Shaaban, Shaimaa El-Ashwah, Alaa Elshamy, Manal Atef, Maged Saafan, Ahmed E. Eladl, Sarah El-Sherpiny, Shaimaa Hendawy, Aya Elbogdady, Mohamed El Bogdady, Basma Atef   +10 more
doaj   +1 more source

Idiopathic multicentric Castleman disease: pathogenesis, clinical presentation and recommendations for treatment based on the Castleman Disease Collaborative Network (CDCN) [PDF]

, 2021
Castleman disease is a very rare, lymphoproliferative disease, driven by dysregulation of the cytokine interleukin 6 (IL-6) and other proinflammatory cytokines with the development of symptoms of systemic inflammation, reactive proliferation of ...
Domańska-Czyż, Katarzyna, Ostrowska, Beata, Romejko-Jarosińska, Joanna, Walewski, Jan   +3 more
core   +2 more sources

Lenalidomideas a Second-line Therapy Achieves Long-term Remission in Elderly Patients with Relapsed/Refractory Multicentric Castleman's Disease：a Report of Two Cases and Literature Review [PDF]

, 2022
No standard therapy is recommended for elderly multicentric Castleman's disease (MCD) patients who failed to the first-line treatment or relapsed. Lenalidomide has been reported to be effective for relapsed/refractory MCD in foreign countries, but ...
TANG Yangming, SHI Renzhou, LAN Mei, LI Xuejun, WEN Zonghua, LU Xiaochen
core   +1 more source

Unicentric Castleman disease presenting as a longstanding axillary and chest wall mass: A case report

Clinical Case Reports, Volume 11, Issue 12, December 2023., 2023
Magnetic resonance imaging (MRI). Key clinical message Unicentric Castleman disease, particularly the hypervascular variant subtype, commonly presents as a localized lymphadenopathy without systemic symptoms. Surgical excision is often curative for this subtype, leading to a good prognosis.
Wenqing Zhou, Xing Liu, Aiming Qiu, Teng Ni, Tiangeng Dong, Lei Ding   +5 more
wiley   +1 more source

Are patients with HHV-8 associated Castleman disease successfully treated with rituximab at risk of subsequently developing HHV-8 negative (idiopathic) Castleman disease? [PDF]

, 2023
Introduction: Multicentric Castleman disease (MCD) is a lymphoproliferative disorder characterized by lymph node histopathology and systemic symptoms.
Bryce Tanaka, Christina Chong, Gavin Ha, Kelsey Kwong, Yoshito Nishimura   +4 more
core   +2 more sources

Unmet Clinical Needs in the Management of Idiopathic Multicentric Castleman Disease: A Consensus‐based Position Paper From an ad hoc Expert Panel

HemaSphere, Volume 7, Issue 6, June 2023., 2023
Castleman disease describes a group of heterogeneous clinicopathological disorders now included in the tumor‐like lesions with B‐cell predominance of the World Health Organization classification. Managing idiopathic multicentric Castleman disease (iMCD) is challenging, because few systematic studies or comparative randomized clinical trials have been ...
Pier Luigi Zinzani, Marco Paulli, Luca Arcaini, Emanuel Della Torre, Simone Ferrero, Amalia Figuera, Ferdinando Frigeri, Maurizio Martelli, Elena Sabattini, Riccardo Scarpa, Giovanni Barosi   +10 more
wiley   +1 more source

A case of TAFRO syndrome with DIC and neurologic and cardiac involvement

Clinical Case Reports, Volume 11, Issue 5, May 2023., 2023
Key Clinical Message We highlight a novel case of TAFRO syndrome with disseminated intravascular coagulation, neurologic changes, and non‐ischemic cardiomyopathy. Through this clinical vignette, we hope to raise awareness of TAFRO syndrome and encourage providers to maintain a high level of suspicion for it when evaluating patients who meet the ...
Lindsay N. Moy, Mauli Patel, Josiah Eschbach, Phillip Knouse, Ángel Gálvez   +4 more
wiley   +1 more source