Results 341 to 350 of about 340,731 (384)
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2008
Imidazoles, benzimidazoles, imidazolines, imidazolidines, and related carbenes are classes of heterocyclic compounds possessing unique chemical and physical properties. Tremendous advances in imidazole chemistry have been made in the decade since 1995, and are manifested in the large body of the literature related to imidazole and its analogs.
Longbin Liu, Qi Huang, Ning Xi
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Imidazoles, benzimidazoles, imidazolines, imidazolidines, and related carbenes are classes of heterocyclic compounds possessing unique chemical and physical properties. Tremendous advances in imidazole chemistry have been made in the decade since 1995, and are manifested in the large body of the literature related to imidazole and its analogs.
Longbin Liu, Qi Huang, Ning Xi
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Biological Significance of Imidazole-Based Analogues in New Drug Development.
Current Drug Discovery Technologies, 2019In the field of heterocyclic medicinal chemistry, especially five membered ring structures containing nitrogen atom, imidazole core is an imperative aromatic heterocycle which is usually present in naturally occurring products and synthetic bioactive ...
Pratiksha Nishant Chopra, J. K. Sahu
semanticscholar +1 more source
Prebiotic synthesis of imidazole-4-acetaldehyde, imidazole-4-glycol and imidazole-4-ethanol
Origins of life and evolution of the biosphere, 1986A wide var iety of chemical processes have been used for the synthesis of amino acids from prebiot ic molecular precursors under plausible pr imi t ive Earth conditions (M i l l e r , 1982). The prebiot ic formation of a l l protein-type amino acids has been demonstrated except for three amino acids: h is t id ine , lys ine, and arginine (Weber and Mi ...
Stanley L. Miller +3 more
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Imidazole: An Essential Edifice for the Identification of New Lead Compounds and Drug Development.
Mini-Reviews in Medical Chemistry, 2018In recent years, a drastic rise has been observed in incidences of resistance, low efficacy rates and toxicities to various drugs used in therapeutic application.
Nishtha Shalmali +2 more
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Condensation of mononucleotides by imidazole
Journal of Molecular Evolution, 1971The condensation of thymidine-5′-monophosphate was carried out in the presence of imidazole in aqueous solutions at neutral pH. Formation of oligo-deoxyribonucleotides up to four units was observed.
J. D. Ibanez, A. P. Kimball, J. Oró
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, 2018
Phosphate diester hydrolysis is strongly accelerated, by a factor of 104, in the presence of artificial enzymes especially designed in the light of spatiotemporal concepts, anchoring imidazoles in a pillar[5]arene matrix.
E. H. Wanderlind +9 more
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Phosphate diester hydrolysis is strongly accelerated, by a factor of 104, in the presence of artificial enzymes especially designed in the light of spatiotemporal concepts, anchoring imidazoles in a pillar[5]arene matrix.
E. H. Wanderlind +9 more
semanticscholar +1 more source
ChemInform Abstract: Superelectrophilic Chemistry of Imidazoles.
ChemInform, 2009AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Robert M. Gallo +7 more
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1984
Publisher Summary This chapter discusses the 4H-imidazoles that have a tetrahedral carbon atom in the ring and thus are nonaromatic. The synthesis of 4H-imidazoles can be done from transformation of imidazolone derivatives, ketones and amidines, imines and amidines, reaction between 1H-imidazoles and electrophiles, azirines, and methods for N-oxides.
Michael P. Sammes, Alan R. Katritzky
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Publisher Summary This chapter discusses the 4H-imidazoles that have a tetrahedral carbon atom in the ring and thus are nonaromatic. The synthesis of 4H-imidazoles can be done from transformation of imidazolone derivatives, ketones and amidines, imines and amidines, reaction between 1H-imidazoles and electrophiles, azirines, and methods for N-oxides.
Michael P. Sammes, Alan R. Katritzky
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Structure of imidazole methemoglobin
Journal of Molecular Biology, 1981Abstract Crystals of horse methemoglobin shatter when soaked in crystallization buffer containing high concentrations of imidazole. By using less than saturating concentrations of imidazole, a stable imidazole derivative of crystalline methemoglobin was prepared and analyzed by X-ray difference Fourier techniques.
Jeffrey A. Bell +2 more
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New complexes of copper cinnamates and imidazole or substituted imidazole
Thermochimica Acta, 1993Abstract We have prepared five new organo-metallic complexes of imidazoles and a dicarboxylate, copper cinnamate, which may be considered as extremely simple models of the active centres in most biocatalysts. The thermal behaviour of the complexes was studied. Using ESR and diffuse reflectance spectra, monomeric or dimeric species were detected.
A. Busnot +3 more
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