Results 101 to 110 of about 49,920 (311)

ヘキサナール刺激でドーパミンを放出した PC12 細胞のドーパミンの再蓄積作用 [PDF]

, 2017
　すべての食品に匂い（香り）がある．食品に含まれる匂い（香り）物質は，食品中の栄養素と同様に体内に取り込まれ，生理作用を示すと考えている． ヘキサナールは炭素数6 の直鎖アルデヒドであり，植物特有の新鮮な香りを構成している物質の1 つである． これまでに，私たちは，ヘキサナールがラット脳線条体切片及びラット副腎褐色細胞腫（PC12）細胞からのドーパミン放出を促進することを報告している． 　ドーパミンを放出した細胞は，次の刺激に応答するために，細胞内にドーパミンを再蓄積する必要がある． 本研究では ...
Kobayashi, Yoko, 小林, 葉子
core  

Role of Glutamate Excitotoxicity in Glioblastoma Growth and Its Implications in Treatment

Cell Biology International, Volume 49, Issue 5, Page 421-434, May 2025.
ABSTRACT Glioblastoma is a highly malignant and invasive type of primary brain tumor that originates from astrocytes. Glutamate, a neurotransmitter in the brain plays a crucial role in excitotoxic cell death. Excessive glutamate triggers a pathological process known as glutamate excitotoxicity, leading to neuronal damage.
Colin Moriarty, Natasha Gupta, Debanjan Bhattacharya   +2 more
wiley   +1 more source

Study of the β-Cyclodextrin Imipramine Hydrochloride Inclusion Complex and Determination of its Stability Constant (K) by UV-Visible Spectroscopy

E-Journal of Chemistry, 2007
In this research, the interactions of imipramine hydrochloride drug with β- cyclodextrin and the stability constant (K) of the inclusion complex formed between them were investigated by using UV-visible spectroscopy.
Alamdar Ashnagar, Nahid Gharib Naseri, Bita Khanaki   +2 more
doaj   +1 more source

Features of reproduction and assisted reproduction in the white (Ceratotherium simum) and black (Diceros bicornis) rhinoceros [PDF]

, 2015
Despite the worldwide increase of rhinoceros calf numbers, the growth of the population of white and black rhinoceros is slowing down mainly due to anthropogenic causes, such as poaching and habitat loss.
Govaere, Jan, Van Soom, Ann, van Zijl Langhout, M, Ververs, Cyrillus   +3 more
core  

Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3(-/-) mice, but not wildtype mice. [PDF]

, 2017
Industrialisation greatly increased human night-time exposure to artificial light, which in animal models is a known cause of depressive phenotypes.
A Harkin, A Khammanivong, A Tapia-Osorio, AE Autry, AM Greco, BH Cline, BJ Martynhak, BJ Martynhak, CA Bolanos, CA Czeisler, CB Filho, D Chaudhury, D Suri, DF Klein, DL McMakin, DM Berson, DR van der Veen, DS Pereira, F Faridhosseini, FK Goodwin, HK Teng, I Lucki, J Aschoff, J Bennie, J Spijker, JF Duffy, JPR Jacobsen, K Suzuki, L van Londen, L Zhang, LK Fonken, LK Fonken, LK Fonken, LP Shearman, M Berk, M Dumont, M Hamilton, M Mazza, M Sturm, MK Hogan, ML Molendijk, MM Gonzalez, O Berton, P D’Aquila, P Georgiou, P Willner, P Zanos, PC Casarotto, PP Mersch, R Refinetti, R Uher, RC Kessler, RD Porsolt, RJ Katz, RM Santiago, RP Snaith, S Pothion, SA Golden, T Ashkenazy-Frolinger, T Cambras, T Kasahara, TA Bedrosian, TA Bedrosian, TA Bedrosian, TA LeGates, TA LeGates, TA Wehr   +66 more
core   +2 more sources

Role of Extracellular Vesicles in the Pathogenesis of Brain Metastasis

Journal of Extracellular Biology, Volume 4, Issue 5, May 2025.
ABSTRACT Extracellular vesicles (EVs) are small particles released by various cells, including cancer cells. They play a significant role in the development of different cancers, including brain metastasis. These EVs transport biomolecular materials such as RNA, DNA, and proteins from tumour cells to other cells, facilitating the spread of primary ...
Muhammad Izhar, Maciej S. Lesniak
wiley   +1 more source

Imipramine in pregnancy. [PDF]

BMJ, 1972
Douglas M. Fleming, D L Crombie, R. J. Pinsent   +2 more
openaire   +7 more sources

Adult hippocampal neuroplasticity triggers susceptibility to recurrent depression [PDF]

, 2017
Depression is a highly prevalent and recurrent neuropsychiatric disorder associated with alterations in emotional and cognitive domains. Neuroplastic phenomena are increasingly considered central to the etiopathogenesis of and recovery from depression ...
A Mateus-Pinheiro, A Mateus-Pinheiro, A Mateus-Pinheiro, A Sahay, A Surget, A Surget, AD Simons, B Czeh, BS McEwen, C Schmidt-Hieber, C Yang, EY Fenton, F Hardeveld, G Dagyte, GS Kirshenbaum, J Fuss, J Fuss, JL Onksen, JM Bessa, JM Bessa, JM Bessa, JY Kim, K McAlonan, K Sim, KG Akers, L Clark, L Santarelli, L Suo, MA Kheirbek, MN Jayatissa, N Kee, N Toni, P Patricio, P Willner, R Bisaz, RJ Baldessarini, RJ Boland, S Ge, SD Hollon, SM Southwick, SW Chan, TD Schmittgen, TI Mueller, YF Li, YH Hsiao, YI Sheline   +45 more
core   +1 more source

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang   +4 more
wiley   +1 more source

Effect of Local and Application of Amitriptyline and Imipramine on Teeth with Irreversible Pulpitis Failed Pulpal Anesthesia: A Randomized, Double-blind, Controlled Trial

Dental Hypotheses, 2016
Introduction: To evaluate the analgesic effect of amitriptyline and imipramine after local application on the dentine of “hot teeth” with failed pulpal anesthesia.
Mohsen Aminsobhani, Naghmeh Meraji, Abdollah Ghorbanzadeh, Majid Ajami, Seied Ali Seiedi Hoseini, Mohammad J Kharazifard   +5 more
doaj   +1 more source