Results 101 to 110 of about 51,042 (305)

Serotonin (5‐Hydroxytryptamine): Metabolism, Signaling, Biological Functions, Diseases, and Emerging Therapeutic Opportunities

open access: yesMedComm, Volume 6, Issue 9, September 2025.
This article reviews the roles of 5‐HT metabolism, 5‐HT receptors, and their related signaling pathways in normal physiology and various diseases, and explores their potential value in disease treatment, providing a reference basis for research and clinical treatment in related fields. ABSTRACT Serotonin (5‐hydroxytryptamine; 5‐HT) is an evolutionarily
Yuxin Zhang   +7 more
wiley   +1 more source

Comparison of Lavandula officinalis tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized pilot study

open access: yesJournal of Medicinal Plants, 2002
Depression is a major health problem and is not only underrecognized and undertreated but is associated with significant morbidity and mortality. Lavandula officinalis is used to treat depression.
M Khani   +5 more
doaj  

Inhibiting extracellular vesicles formation and release: a review of EV inhibitors

open access: yesJournal of Extracellular Vesicles, 2020
It is now becoming well established that vesicles are released from a broad range of cell types and are involved in cell-to-cell communication, both in physiological and pathological conditions.
Mariadelva Catalano   +1 more
doaj   +1 more source

Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia [PDF]

open access: yes, 2013
journal ...
HAN Jun kyu   +5 more
core   +1 more source

Neural circuitry of rapid eye movement sleep homeostasis: Mechanistic insights and pathological implications

open access: yesSleep Research, Volume 2, Issue 3, Page 128-144, September 2025.
Abstract Rapid eye movement (REM) sleep is a unique brain state crucial for emotion, memory, and plasticity. Unlike well‐understood non‐REM (NREM) sleep homeostasis, REM sleep homeostasis remains less clearly defined. This review highlights recent progress in understanding REM sleep homeostasis, focusing on its neurophysiological markers, neural ...
Ting He
wiley   +1 more source

A randomized controlled trial of imipramine in patients with irritable bowel syndrome.

open access: yesWorld Journal of Gastroenterology, 2009
AIM To study the efficacy of low-dose imipramine in relieving symptoms associated with the irritable bowel syndrome (IBS). METHODS A randomized, double-blind trial of 25 mg imipramine vs matched placebo for 12 wk was performed.
Heitham Abdul‐Baki   +7 more
semanticscholar   +1 more source

Determination of fluphenazine, related phenothiazine drugs and metabolites by combined high-performance liquid chromatography and radioimmunoassay. [PDF]

open access: yes, 1981
Antibodies have been produced in rabbits immunized with a fluphenazine succinate-human serum albumin conjugate. By radioimmunoassay it is possible to quantify fluphenazine (FPZ), related phenothiazine drugs and several of their metabolites at the ...
Goldstein, SA, Van Vunakis, H
core  

Preclinical discovery of duloxetine for the treatment of depression [PDF]

open access: yes, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María   +4 more
core   +2 more sources

Acquired narcolepsy secondary to a presumptive hypothalamic hamartoma in a young German wirehaired pointer dog

open access: yesVeterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract A 3‐year‐old, male, entire, German wirehaired pointer dog was presented with a 2‐year history of paroxysmal episodes of collapse associated with reduced levels of consciousness. A magnetic resonance imaging study identified a single, ill‐defined, non‐contrast‐enhancing, intra‐axial mass lesion involving the hypothalamus.
Callum Atkins   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy